Table 7.

Regions showing evidence of supporting mental state and harm integration by means of the contrast (Stage C > Stage B) > (Stage B > Stage A)a

RegionTalairach coordinatestpSizeSuperadditive harm × MS interactionPunishment decoding (C)
R middle occipital gyrus39−7014.46<1.0E-6340.001.00−0.060.96
R DLPFC3032404.10<1.0E-6263.090.100.760.45
R amygdala24−13−145.53<1.0E-67212.46<1.0E-6b−0.490.63
L amygdala−21−7−206.53<1.0E-6527.840.01b−0.410.69
  • aWhole-brain contrast corrected at q(FDR) = 0.05. Superadditive harm × MS interaction column shows statistics for an ROI-based analysis in each region identifying patterns consistent with a superadditive interaction similar to that displayed in the behavioral results and a nonspecific mental state × harm interaction, respectively. Punishment decoding (C) reports the significance of MVPA decoding of punishment amount during Stage C in each of these regions compared with chance. All ROI analyses corrected for multiple comparisons. The PCC region is rostral to and does not overlap with the region identified in the mental state > harm contrast (compare Figs. 3A, 5A; Tables 3, 5, 7), just as the present MPFC region does not overlap with the left MPFC region identified in the whole-brain linear effect of mental state analysis (compare Tables 6 and 7).

  • bStatistically significant interaction effect.