Control measures collected from mouse oddity experiments for each condition
| Experiment | Condition | Total object exploration |
|---|---|---|
| TAC-VIS MSO + controls (TAC and VIS only): systemic ketamine in wildtype mice | VEH (TAC-VIS) | 14.35 ± 1.29 |
| VEH (TAC) | 23.02 ± 3.77 | |
| VEH (VIS) | 11.57 ± 1.28 | |
| KET (TAC-VIS) | 20.70 ± 1.32 | |
| KET (TAC) | 26.80 ± 3.17 | |
| KET (VIS) | 15.31 ± 1.52 | |
| TAC-VIS MSO: CNO in wildtype mice | VEH | 9.45 ± 1.80 |
| CNO | 6.96 ± 1.36 | |
| TAC-VIS MSO + controls (TAC and VIS only): systemic CNO in PV-Cre mice | VEH (TAC-VIS) | 24.15 ± 1.92 |
| VEH (TAC) | 24.18 ± 1.60 | |
| VEH (VIS) | 19.14 ± 2.14 | |
| CNO (TAC-VIS) | 27.37 ± 2.65 | |
| CNO (TAC) | 23.88 ± 1.67 | |
| CNO (VIS) | 17.17 ± 1.33 | |
| TAC-VIS MSO: systemic CNO + systemic ABT-418 in PV-Cre mice | VEH/VEH | 16.46 ± 1.63 |
| VEH/ABT | 15.49 ± 2.12 | |
| CNO/VEH | 19.31 ± 1.70 | |
| CNO/ABT | 17.34 ± 2.23 |
Data are expressed as the mean ± SEM of the total time in seconds spent exploring the objects.
KET, Ketamine; TAC, tactile; VIS, visual.