Network metric | ||||
---|---|---|---|---|
Degree | Strength | Clustering | Efficiency | |
Controls | 106.52 ± 36.07 | 22.97 ± 8.90 | 0.14 ± 0.01 | 0.27 ± 0.04 |
General LD | 105.60 ± 40.40 | 23.27 ± 10.11 | 0.15 ± 0.02 | 0.27 ± 0.03 |
p | 0.97 | 0.94 | 0.0001* | 0.99 |
Familial LD (ABLD + ADLD) | 106.44 ± 37.23 | 23.56 ± 9.27 | 0.14 ± 0.02 | 0.28 ± 0.04 |
Sporadic LD (ABLD + ADLD) | 106.16 ± 39.54 | 23.02 ± 9.70 | 0.14 ± 0.02 | 0.27 ± 0.02 |
p | 0.99 | 0.79 | 0.85 | 0.23 |
ADLD (Sporadic only) | 106.24 ± 40.26 | 22.64 ± 9.71 | 0.14 ± 0.02 | 0.26 ± 0.03 |
ABLD (Sporadic only) | 105.54 ± 39.89 | 23.89 ± 10.32 | 0.15 ± 0.01 | 0.28 ± 0.03 |
p | 0.98 | 0.35 | 0.0001* | 0.07 |
Familial LD (ADLD only) | 105.78 ± 36.33 | 23.91 ± 9.31 | 0.14 ± 0.02 | 0.28 ± 0.02 |
Sporadic LD (ADLD only) | 105.95 ± 38.23 | 23.40 ± 9.62 | 0.14 ± 0.01 | 0.27 ± 0.03 |
p | 0.99 | 0.82 | 0.91 | 0.21 |
ADLD (Sporadic + familial) | 106.45 ± 40.12 | 22.70 ± 9.66 | 0.14 ± 0.02 | 0.27 ± 0.03 |
ABLD (Sporadic + familial) | 105.87 ± 40.25 | 23.60 ± 10.15 | 0.15 ± 0.02 | 0.28 ± 0.03 |
p | 0.98 | 0.57 | 0.001* | 0.16 |
Degree, strength, and clustering coefficient values are given as averages (mean ± SD) of nodal values across the respective group-averaged network. Efficiency was estimated by averaging the global efficiency of per-subject networks in the respective group.
↵*Statistically significant differences in the associated network metrics between the analyzed groups at p ≤ 0.05 adjusted for multiple comparisons using a single-step correction of the maximal test statistic in a 2-tailed permutation test.