Table 2.

Description of the experimental animal groups, the viral vectors used, and the viral vector dose injected in the two overexpression experiments

VirusLow-dose RGMa overexpressionHigh-dose RGMa overexpression
AAV2/7-RGMa, AAV2/7-Empty, AAV2/7-GFP, salineAAV2/7-RGMa unilateral, AAV2/7-RGMa bilateral, AAV2/7-Empty
Titer3.0 × 10129.0 × 1012
No. of animals per groupN = 7–8, for saline N = 6N = 6
Survival time (wk)1218.5