Psychiatric disorder | Adult females | Adult males | ||||||
---|---|---|---|---|---|---|---|---|
Case patients | Control subjects | OR | p value | Case patients | Control subjects | OR | p value | |
ADHD | 54 | 13,561 | 1.24 | 0.3745 | 46 | 11,371 | 2.09 | 0.0014 |
Pervasive developmental disorders (ASDs) | 66 | 13,561 | 1.21 | 0.4067 | 61 | 11,371 | 1.91 | 0.0018 |
Schizophrenia | 47 | 8478 | 0.97 | 0.9260 | 29 | 8404 | 0.39 | 0.0683 |
Suicidal ideation or attempt | 48 | 8478 | 1.18 | 0.5325 | 55 | 8404 | 0.58 | 0.0872 |
Antisocial/borderline personality disorder | 39 | 8478 | 0.92 | 0.7924 | 14 | 8404 | 0.19 | 0.1061 |
Suicidal ideation | 26 | 8478 | 1.53 | 0.1970 | 30 | 8404 | 0.48 | 0.1108 |
Major depressive disorder | 499 | 8478 | 1.08 | 0.3699 | 273 | 8404 | 1.18 | 0.1328 |
Psychogenic and somatoform disorders | 92 | 8478 | 0.84 | 0.4269 | 21 | 8404 | 0.41 | 0.1331 |
Agoraphobia, social phobia, and panic disorder | 121 | 8478 | 1.17 | 0.3423 | 54 | 8404 | 0.66 | 0.1717 |
Transient alteration of awareness | 48 | 11202 | 0.81 | 0.4855 | 31 | 9205 | 0.58 | 0.1989 |
Obsessive-compulsive disorders | 30 | 8478 | 0.90 | 0.7733 | 17 | 8404 | 1.58 | 0.2542 |
Personality disorders | 66 | 8478 | 0.86 | 0.5331 | 32 | 8404 | 0.64 | 0.2689 |
Generalized anxiety disorder | 189 | 8478 | 0.84 | 0.2440 | 101 | 8404 | 1.22 | 0.2700 |
Other specified nonpsychotic and/or transient mental disorders | 612 | 11,202 | 1.04 | 0.6052 | 630 | 9205 | 0.92 | 0.3314 |
Posttraumatic stress disorder | 134 | 8478 | 1.03 | 0.8740 | 55 | 8404 | 1.24 | 0.3703 |
Eating disorder | 35 | 8478 | 1.50 | 0.1554 | 6 | 8404 | 1.72 | 0.4136 |
Anxiety, phobic and dissociative disorders | 1968 | 8478 | 1.00 | 0.9188 | 950 | 8404 | 0.95 | 0.4144 |
Anxiety disorder | 1559 | 8478 | 0.95 | 0.3228 | 731 | 8404 | 0.95 | 0.4749 |
Aphasia/speech disturbance | 242 | 11,202 | 1.18 | 0.1526 | 237 | 9205 | 0.91 | 0.4904 |
Bipolar | 226 | 8478 | 0.74 | 0.0350 | 152 | 8404 | 1.10 | 0.5250 |
Dysthymic disorder | 419 | 8478 | 1.10 | 0.3009 | 177 | 8404 | 0.93 | 0.6514 |
Mental retardation | 48 | 13,561 | 0.87 | 0.6415 | 48 | 11,371 | 0.92 | 0.7791 |
Depression | 2370 | 8478 | 1.04 | 0.3252 | 1276 | 8404 | 0.99 | 0.8735 |
Mood disorders | 2565 | 8478 | 1.04 | 0.4239 | 1435 | 8404 | 1.00 | 0.9278 |
Conduct disorders | 36 | 13,561 | 0.92 | 0.8067 | 42 | 11,371 | 0.99 | 0.9675 |
Odds ratios (ORs) are reported as increased risk for the rare allele Pro33. p values are presented as raw, uncorrected values. Italics is used to indicate disorders with statistically significant associations.