Table 1.

Summary of pharmacological effects on SRCaTs tested in the screening round

Drug nameConcentration (μm)nEarly DMI (%)SD (%)pLate DMI (%)SD (%)I
TTX114128520.06251921690.0621
Nimodipine10255640<0.00014847<0.0001
FPL 6417625161781460.04781581030.0396
Diltiazem200721230.00017.216<0.0001
Thapsigargin10121181150.600669570.0866
Ryanodine206119490.3822125660.3965
ω-Conotoxin MVIIC2016142560.00981441180.1576
CNQX1011108630.6820110710.6641
D-APV509167810.0385147760.1026
EGTA200043.01.6<0.00010.20.3<0.0001
  • Values in bold reached statistical significance (p < 0.05).