Table 2.

Behavioral data for preoperative and postoperative testing sessions

CaseVehicle: correct, % (SD)Pre-op/Post-opDrug (dose, mg/kg)Correct, %t statistic (p value)
A82.3 (13.3)Post-opCNO (10)83.30.07 (0.47)
Post-opCNO (20)83.30.07 (0.47)
Post-opCNO (20)87.60.38 (0.35)
B86.4 (8.5)Post-opCNO (10)83.3−0.35 (0.37)
Post-opCNO (20)70.8−1.79 (0.04)
Post-opCNO (20)54.2−3.70 (0.001)
Post-opCNO (20)58.3−3.22 (0.002)
Post-opCNO (20)87.50.13 (0.45)
P73.5 (7.8)Pre-opCNO (20)70.8−0.33 (0.37)
Post-opCNO (20)58.3−1.87 (0.04)
Post-opCNO (20)58.3−1.87 (0.04)
Post-opCNO (10)62.5−1.36 (0.10)
Post-opCNO (20)70.8−0.33 (0.37)
Post-opCNO (20)75.00.19 (0.43)
T86.1 (5.3)Pre-opC21 (20)96.01.78 (0.05)
Pre-opCNO (24.5)92.01.066 (0.16)
Post-opCNO (20)93.31.30 (0.11)
Post-opCNO (20)56.7−5.27 (<0.0005)
Post-opCNO (20)93.31.30 (0.11)
Post-opC21 (20)80.0−1.09 (0.15)
Post-opC21 (20)76.7−1.69 (0.06)
Post-opC21 (20)90.00.71 (0.25)
Z95.8 (5.6)Pre-opCNO (20)83.3−2.14 (0.03)
Post-opCNO (20)91.7−0.71 (0.25)
Post-opCNO (20)100.00.72 (0.25)
  • All sessions for each case are in chronological order. C21, Compound 21.