Passive membrane properties of neurons in PFC
| Cell type | Genotype | Capacitance (pF) | Membrane resistance (mΩ) | Rest (mV) | Pipette resistance (mΩ) | Access resistance (mΩ) |
|---|---|---|---|---|---|---|
| Fast spiking interneurons | WT–VEH | 29.94 ± 1.32 | 254.58 ± 19.53 | 65.17 ± 0.72 | 3.77 ± 0.16 | 15.7 ± 0.86 |
| WT–TAM | 28.71 ± 1 | 242.64 ± 23.08 | 67.53 ± 1.02 | 3.9 ± 0.16 | 15 ± 0.79 | |
| AS–VEH | 30.2 ± 2.1 | 254.2 ± 15.92 | 66.07 ± 0.83 | 4.01 ± 0.14 | 16.86 ± 1.54 | |
| AS–TAM | 27.69 ± 0.85 | 245.84 ± 26.75 | 66.72 ± 0.75 | 3.71 ± 0.1 | 14.64 ± 10.48 | |
| Layer 5 pyramidal neurons | WT–VEH | 138.84 ± 5.91 | 185.4 ± 17.96 | 65.05 ± 0.44 | 3.76 ± 0.13 | 14.78 ± 0.60 |
| WT–TAM | 132.35 ± 7.08 | 153.2 ± 7.08 | 66.02 ± 0.98 | 3.67 ± 0.12 | 15.63 ± 7.08 | |
| AS–VEH | 141.96 ± 5.08 | 200.35 ± 16.75 | 65.79 ± 0.63 | 3.58 ± 0.16 | 14.64 ± 0.63 | |
| AS–TAM | 122.13 ± 5.98 | 161.77 ± 11.72 | 65.05 ± 0.77 | 4.15 ± 0.15 | 16.45 ± 0.84 | |
| Layer 3 pyramidal neurons | WT–VEH | 101.84 ± 5.10 | 308.37 ± 25.57 | 69.74 ± 0.77 | 3.33 ± 0.13 | 15.78 ± 1.37 |
| WT–TAM | 118.54 ± 7.6 | 323.20 ± 29.3 | 68.94 ± 0.65 | 3.85 ± 0.09 | 14.33 ± 1.16 | |
| AS–VEH | 103.6 ± 0.22 | 328.51 ± 34.88 | 69.06 ± 1.25 | 3.71 ± 0.22 | 14.74 ± 2.14 | |
| AS–TAM | 102.9 ± 5.7 | 313.76 ± 35.2 | 67.68 ± 0.75 | 3.89 ± 0.15 | 14.52 ± 1.23 |