Those regions showing significantly greater GMV in 14 year olds reporting 1 or 2 instances of cannabis use than in matched controls
| Anatomical region (AAL) | No. of significant voxels | Anatomical region implicated, % |
|---|---|---|
| Cluster 1: left temporal (Vol. 4968 vox; 16,767 μl; F(1,80) = 8.88, pcorr = 0.008; peak voxel −55, −2, −14) | ||
| Frontal lobe | ||
| Olfactory cortex | 136 | 20.57 |
| Gyrus rectus | 48 | 2.33 |
| Superior frontal gyrus (pars orbitalis) | 29 | 1.34 |
| Inferior frontal gyrus (pars orbitalis) | 39 | 0.95 |
| Temporal lobe | ||
| Superior temporal gyrus | 420 | 7.87 |
| Middle temporal gyrus | 164 | 1.38 |
| Heschl's gyrus | 3 | 0.55 |
| Superior temporal pole | 13 | 0.43 |
| Rolandic operculum | 5 | 0.21 |
| Inferior temporal gyrus | 5 | 0.07 |
| Subcortical | ||
| Amygdala | 382 | 74.17 |
| Hippocampus | 777 | 35.63 |
| Putamen | 503 | 21.13 |
| Pallidum | 126 | 18.13 |
| Insula | 640 | 14.79 |
| ParaHippocampal gyrus | 202 | 8.56 |
| Caudate | 92 | 4.08 |
| Cluster 2: Right temporal (Vol. 3710 vox; 12,491 μl); F(1,80) = 5.88, pcorr = 0.018; peak voxel 30, −11, −27) | ||
| Temporal lobe | ||
| Heschl's gyrus | 68 | 11.62 |
| Superior temporal gyrus | 50 | 0.67 |
| Superior temporal pole | 17 | 0.54 |
| Subcortical | ||
| Amygdala | 439 | 73.91 |
| Hippocampus | 746 | 33.13 |
| Pallidum | 172 | 26.46 |
| Putamen | 564 | 22.20 |
| Parahippocampal gyrus | 410 | 15.61 |
| Insula | 185 | 4.39 |
| Cluster 3: Bilateral Posterior (Vol. 4959 vox; 16,737 μl); F(1,80) = 14.32, pcorr = 8.0 × 10−4; peak voxel −24, −59, 3) | ||
| Temporal lobe | ||
| Fusiform gyrus (L) | 283 | 5.18 |
| Fusiform gyrus (R) | 114 | 1.91 |
| Parietal lobe | ||
| Posterior cingulate (R) | 59 | 7.98 |
| Posterior cingulate (L) | 22 | 1.97 |
| Precuneus (R) | 268 | 3.45 |
| Precuneus (L) | 212 | 2.55 |
| Occipital lobe | ||
| Lingual gyrus (R) | 1158 | 21.14 |
| Lingual gyrus (L) | 818 | 16.01 |
| Calcarine (L) | 269 | 5.16 |
| Calcarine (R) | 79 | 1.87 |
| Cerebellum | ||
| Cerebellar vermis (4 5) | 258 | 17.61 |
| Cerebellar lobule 4 5 (R) | 308 | 14.62 |
| Cerebellar lobule 6 (L) | 332 | 8.20 |
| Cerebellar lobule 6 (R) | 265 | 6.18 |
| Cerebellar lobule 4 5 (L) | 156 | 5.80 |
| Cerebellar vermis (6) | 7 | 0.88 |
| Crus cerebellum1 (L) | 8 | 0.13 |