Table 3.

Basal dopamine levels in the NAc as detected by in vivo microdialysis

ShamPNIPNI + JDTic
0.209380.027280.10100
0.229820.121250.21516
0.128380.051750.48927
0.124421.326250.79104
0.658620.310250.47336
0.081820.23101
0.63812
  • Mice underwent sham or PNI to induce neuropathic pain 14 d prior to assessing basal dopamine levels by in vivo microdialysis. JDTic was administered 24 h prior to conducting microdialysis measurements. Each data point is a mean of eight measurements taken consecutively in 5 min samples. Data are raw data values. N = 5–7 per group. One-way ANOVA showed no difference between groups: F(2,15) = 0.4558, p = 0.642.