DMH VGAT WT | DMH VGAT KO | |||||
---|---|---|---|---|---|---|

Ad libitum | O/N Fast | Re-fed | Ad libitum | O/N Fast | Re-fed | |

Input resistance, MΩ | 809 ± 52 | 797 ± 48 | 758 ± 33 | 735 ± 46 | 776 ± 59 | 728 ± 48 |

Membrane potential, mV | −59 ± 2.3 | −62 ± 2.8 | −63 ± 2.5 | −60 ± 3.4 | −59 ± 5.6 | −58 ± 2.9 |

The input resistance measured from POMC cells was not altered following deletion of VGAT in the DMH (

*F*_{(1,99)}= 1.196,*p*= 0.28; two-way ANOVA) or by challenges to the animal's energy state (*F*_{(2,99)}= 0.369,*p*= 0.69; two-way ANOVA). Deletion of VGAT in the DMH (*F*_{(1,99)}= 0.282,*p*= 0.59; two-way ANOVA), or energy state challenges (*F*_{(2,99)}= 0.016,*p*= 0.98; two-way ANOVA) did not affect the membrane potential of POMC cells. Data are presented as mean ± SEM.