Table 5.

Age-related changes in amygdala activity in the PNC sample using coordinates from previous studiesa

RegionEmotionF(1,754)pEffect size
Right amygdala in Gee et al. (2013)Neutral1.1210.290−0.040
Fear0.2280.6330.018
Anger0.1740.677−0.016
Sad1.9650.1610.052
Happy0.1090.741−0.012
Left amygdala in Kujawa et al. (2016)bNeutral0.9530.3290.036
Fear12.6170.00040.132
Anger1.8440.1750.051
Sad15.1400.00010.144
Happy9.0200.0030.111
Right amygdala in Kujawa et al. (2016)bNeutral0.5660.4520.028
Fear2.6500.1040.061
Anger0.1230.7260.013
Sad2.8010.0950.063
Happy0.7260.3940.032
Left amygdala (AAL) in Wu et al. (2016)bNeutral1.5830.2090.047
Fear15.7967.73e-050.147
Anger4.5710.0330.080
Sad20.7556.08e-060.168
Happy10.0090.0020.117
Right amygdala (AAL) in Wu et al. (2016)bNeutral0.2770.5990.020
Fear5.7410.0170.089
Anger1.9460.1630.052
Sad5.7840.0160.089
Happy1.5530.2130.046
  • aEffect size is measured by the standardized partial coefficient of the age term. AAL, Automated anatomical labeling; ↓, developmental decreases in amygdala with mPFC was reported in the cited study. AAL indicates that the amygdala ROI was derived based on AAL atlas.

  • bNo significant developmental changes were found in the cited study.