Table 1.

A/N ratios, NMDA current decay time constants (τ), CVs of EPSCs at −70 mV, and PPRs in six targets of VPVGluT2 neurons in saline and cocaine-withdrawn mice

A/N ratioNMDA τ (ms)CVPPR
SalineCocaineSalineCocaineSalineCocaineSalineCocaine
VPVGluT22.34 ± 1.191.27 ± 0.45358.6 ± 82164.5 ± 1140.16 ± 0.220.12 ± 0.110.70 ± 0.20.75 ± 0.17
(6/4)(8/4)(6/4)(8/4)(13/6)(9/4)(13/6)(9/4)
VPGABA0.76 ± 0.100.48 ± 0.20136.4 ± 124190.2 ± 1150.19 ± 0.10.28 ± 0.200.67 ± 0.120.77 ± 0.25
(6/4)(6/6)(6/4)(6/6)(11/5)(7/6)(11/5)(7/6)
VTAGABA0.64 ± 0.240.63 ± 0.27126.7 ± 115134.7 ± 410.16 ± 0.070.09 ± 0.020.77 ± 0.160.55 ± 0.08
(6/3)(4/3)(6/3)(4/3)(6/3)(4/3)(6/3)(4/3)
VTADA0.91 ± 0.290.43 ± 0.28131.4 ± 12209.1 ± 1850.17 ± 0.060.18 ± 0.090.75 ± 0.320.71 ± 0.25
(5/2)(4/4)(5/2)(4/4)(4/2)(5/4)(4/2)(5/4)
MDT1.19 ± 0.120.82 ± 0.3341.31 ± 27.965.52 ± 39.40.19 ± 0.120.21 ± 0.150.44 ± 0.210.59 ± 0.33
(4/2)(5/2)(4/2)(5/2)(4/2)(8/3)(4/2)(8/3)
LHb1.55 ± 0.333.84 ± 1.533.61 ± 11.334.55 ± 40.20.26 ± 0.100.15 ± 0.090.76 ± 0.220.54 ± 0.17
(5/3)(6/3)(5/3)(6/3)(6/3)(10/5)(6/3)(10/5)
  • Numbers in parentheses represent the number of cells/number of mice.