Table 1.

Summary of basic electrophysiological properties of TIDA neurons in nulliparous and lactating femalesa

NulliparousLactatingStatep
Cell capacitance19.7 ± 2.720.3 ± 3.0p = 0.88
Membrane potential (mV)
ConditionControl−51.4 ± 0.9−42.74 ± 3.3Main effect of states: p = 0.018*
Conditions: p = 0.041*
ZD−51.2 ± 0.5−44.6 ± 2.8Interaction: p = 0.046*
Input resistance (GΩ)
ConditionControl0.7 ± 0.2−2.1 ± 0.5Main effects of state: p = 0.046*
ZD0.6 ± 0.2−3.5 ± 1.4Conditions: p = 0.262
Interaction: p = 0.19
  • aBaseline electrophysiological properties of TIDA neurons in nulliparous and lactating females before and during ZD7288 application. Experiments were performed in the presence of TTX. Data are mean ± SEM; n = 5 for each group.

  • *Two-way ANOVA and Sidak's test as a post hoc test (p < 0.05).