Clinical and demographic information
| Characteristics | AN (n = 22) | BN (n = 33) | HC (n = 30) | Analysis | ||||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | Χ2(df), F(df), W, t(df) | p Value | |
| Age (years) | 24.6 | 4.7 | 23.6 | 3.9 | 23.9 | 3.5 | Χ2(2) = 0.8 | 0.69 |
| BMI (kg/m2) | 16.4 | 1.4 | 22.0 | 2.4 | 21.9 | 2.1 | Χ2(2) = 48.4 | <0.001 |
| IQa | 116 | 5 | 114 | 5 | 114 | 5 | Χ2(2) = 3.2 | 0.21 |
| Age of onset (years) | 15.6 | 2.4 | 16.2 | 3.1 | t(51.8) = −0.8 | 0.42 | ||
| Illness duration (years) | 9.0 | 5.8 | 7.4 | 4.0 | t(34.4) = 1.1 | 0.27 | ||
| Beck Depression Inventory | 35.3 | 12.0 | 32.7 | 10.5 | 2.4 | 2.8 | Χ2(2) = 57.7 | <0.001 |
| Trait Anxiety Inventory | 63.1 | 10.4 | 62.8 | 7.3 | 33.0 | 6.9 | F(2) = 151.1 | <0.001 |
| Barratt Impulsiveness Scale | 66.2 | 14.0 | 68.4 | 11.1 | 56.7 | 6.3 | F(2) = 10.4 | <0.001 |
| Eating Disorder Examination Questionnaire | 4.4 | 0.8 | 4.6 | 0.8 | 0.2 | 0.2 | Χ2(2) = 58.0 | <0.001 |
| Eating disorder examination ratingsb | ||||||||
| Objective binge-eating episodes | 38.1 | 47.9 | 23.0 | 29.1 | W = 317.5 | 0.43 | ||
| Subjective binge-eating episodes | 9.5 | 12.8 | 6.6 | 6.2 | W = 341.5 | 0.93 | ||
| Vomiting episodes | 43.5 | 51.6 | 24.2 | 31.0 | W = 304.0 | 0.31 | ||
| Laxative episodes | 1.1 | 3.4 | 2.0 | 3.9 | W = 421.5 | 0.18 | ||
| Exercise episodes | 7.4 | 13.6 | 10.9 | 9.4 | W = 478.5 | 0.04 | ||
| N | % | N | % | N | % | Χ2(df) | p Value | |
| Comorbid diagnoses | ||||||||
| Anxiety disorder | 3 | 13.6 | 3 | 9.1 | Χ2(1) = 0.3 | 0.69 | ||
| Major depressive episode | 15 | 68.2 | 16 | 48.5 | Χ2(1) = 2.1 | 0.15 | ||
| Personality disorder | 2 | 9.1 | 5 | 15.2 | Χ2(1) = 0.4 | 0.69 | ||
| Any current treatment | 13 | 59.0 | 15 | 45.5 | Χ2(1) = 1.0 | 0.32 | ||
| Psychotherapy | 9 | 40.9 | 9 | 27.3 | Χ2(1) = 1.1 | 0.29 | ||
| Medication | 10 | 45.5 | 10 | 30.3 | Χ2(1) = 1.3 | 0.25 | ||
| Prior restrictive AN | 14 | 63.6 | 10 | 30.3 | Χ2(1) = 6.0 | 0.01 | ||
Group differences were evaluated using one-way ANOVA and, for non-normally distributed data, the nonparametric Kruskal–Wallis test. The two-samples t test (two-sided), Mann–Whitney U test, and χ2 test were used to assess differences between AN and BN groups. For type and dose of prescribed medications, see Extended data Table 1-1.
↵aEstimated full-scale IQ from the National Adult Reading Test.
↵bED examination ratings reflect counts over the previous 28 d.