Males | Females | |||||
---|---|---|---|---|---|---|
Vertical counts | Stereotypy | %Thigmotaxis | Vertical counts | Stereotypy | %Thigmotaxis | |
Gng7fl/fl | 1305 ± 125 | 18671 ± 1079 | 66.5 ± 1.2 | 1214 ± 124 | 14107 ± 900 | 71.4 ± 1.8 |
Gng7fl/flD1Cre+ | 1090 ± 92 | 18463 ± 799 | 67.6 ± 1.5 | 1127 ± 112 | 14387 ± 961 | 72.1 ± 2.1 |
Gng7fl/fl | 1080 ± 94 | 18893 ± 986 | 69.8 ± 1.2 | 1198 ± 100 | 15872 ± 888 | 72 ± 1.3 |
Gng7fl/flD2Cre+ | 1809 ± 122*** | 24966 ± 1227*** | 71.1 ± 1.1 | 1940 ± 233** | 21084 ± 639*** | 74.1 ± 1.2 |
↵aData are mean ± SEM; n = 14-21 mice/group. Average of cumulative vertical counts and stereotypic counts and % thigmotaxis (100* Σ distance periphery/Σ tot distance) over the 2 h testing period by male and female Gng7fl/flD1Cre+ mice, Gng7fl/flD2Cre+ mice, and relative littermate controls.
↵**p < 0.01,
↵***p < 0.001, indicate significant difference between Gng7fl/flD2Cre+ mice and relative Gng7fl/fl WT littermates (Student's t test).