Table 1.

Statistical Analyses

Figure/statistical testNumber of mice (as appear in graph)Factorial effectsInteraction effect
Overall effects for Figure 1
Factor “treatment”
1AOne-way ANOVAn = 7, 7, 7, 6, 7, 7F(5,35) = 4.10;p = 0.005
Factor “treatment”Factor “CSDS phase”Factor “treatment” × “CSDS phase”
1BTwo-way RM ANOVAn = 8, 6, 7F(2,19) = 1.288;p = 0.299F(2,38) = 84.300;p < 0.0001F(4,38) = 2.737;p = 0.043
Overall effects for Figure 2
Factor “pretreatment”Factor “treatment”Factor “pretreatment” × “treatment”
2ATwo-way ANOVAn = 13, 13, 13, 14F(1,48) = 3.333;p = 0.074F(1,48) = 5.134;p = 0.028F(1,48) = 1.742;p = 0.193
2BTwo-way ANOVAn = 16, 16, 17, 17F(1,62) = 2.900;p = 0.094F(1,62) = 4.625;p = 0.035F(1,62) = 5.317;p = 0.025
Factor “treatment” × “phase”Factor “pretreatment” × “treatment”Factor “pretreatment” × “treatment” × “phase”
2CThree-way RM ANOVAn = 6, 6, 7, 6F(2,42) = 2.316;p = 0.111F(1,21) = 6.452;p = 0.019F(2,42) = 3.278;p = 0.048
Factor “pretreatment”Factor “treatment”Factor “pretreatment” × “treatment”
2DTwo-way ANOVAn = 8, 9, 9, 9F(1,31) = 4.109;p = 0.051F(1,31) = 3.230;p = 0.082F(1,31) = 7.313;p = 0.011
Factor “co-treatment”Factor “treatment”Factor “pretreatment” × “treatment”
2ETwo-way ANOVAn = 7, 9, 8, 8F(1,28) = 10.020;p = 0.004F(1,28) = 7.631;p = 0.010F(1,28) = 7.606;p = 0.010
Overall effects for Figure 3
Factor “pretreatment”Factor “treatment”Factor “pretreatment” × “treatment”
3ATwo-way ANOVAn = 8, 9, 8, 9F(1,30) = 6.804;p = 0.014F(1,30) = 43.040;p < 0.0001F(1,30) = 6.202;p = 0.019
3BTwo-way ANOVAn = 8, 9, 9, 9F(1,31) = 5.795;p = 0.022F(1,31) = 5.261;p = 0.029F(1,31) = 9.041;p = 0.005
3CTwo-way ANOVAn = 8, 8, 9, 8F(1,29) = 6.209;p = 0.019F(1,29) = 3.499;p = 0.072F(1,29) = 6.077;p = 0.020
3DTwo-way ANOVAn = 11, 8, 11, 10F(1,36) = 11.060;p = 0.002F(1,36) = 44.570;p < 0.0001F(1,36) = 19.760;p < 0.0001
3ETwo-way ANOVAn = 8, 10, 7, 10F(1,35) = 5.753;p = 0.022F(1,35) = 6.958;p = 0.012F(1,35) = 3.737;p = 0.061
3FTwo-way ANOVAn = 8, 7, 10, 8F(1,29) = 9.865;p = 0.004F(1,29) = 7.547;p = 0.010F(1,29) = 11.540;p = 0.002
Overall effects for Figure 4
Factor “treatment”
4AOne-way ANOVAn = 8, 8, 8F(2,21) = 15.28;p < 0.0001
Factor “pretreatment”Factor “treatment”Factor “pretreatment” × “treatment”
4BTwo-way ANOVAn = 8, 7, 7, 8F(1,26) = 16.410;p < 0.001F(1,26) = 7.356;p = 0.012F(1,26) = 5.937;p = 0.022
4DTwo-way ANOVAn = 10, 10, 10, 10F(1,36) = 4.468;p = 0.042F(1,36) = 1.963;p = 0.170F(1,36) = 3.944;p = 0.054
4ETwo-way ANOVAn = 10, 10, 10, 10F(1,36) = 1.253;p = 0.270F(1,36) = 4.389;p = 0.043F(1,36) = 2.729;p = 0.107
4HTwo-way ANOVAn = 8, 5, 5, 6F(1,20) = 11.630;p = 0.003F(1,20) = 4.616;p = 0.044F(1,20) = 6.246;p = 0.021
Overall effects for Figure 5
Factor “pretreatment”Factor “treatment”Factor “pretreatment” × “treatment”
5ATwo-way ANOVAn = 6, 7, 7, 7, 7, 7F(2,35) = 1.320;p = 0.280F(1,35) = 7.287;p = 0.011F(2,35) = 4.796;p = 0.014
Factor “treatment”
5BOne-way ANOVAn = 6, 6, 6, 7, 7F(4,27) = 2.469;p = 0.069
5COne-way ANOVAn = 8, 8, 8, 8, 8F(4,35) = 2.469;p = 0.088
5DOne-way ANOVAn = 9, 8, 8, 8, 7, 8F(5,42) = 2.110;p = 0.083