α-synuclein

Research Articles, Neurobiology of Disease
Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology
David H. Adamowicz, Subhojit Roy, David P. Salmon, Douglas R. Galasko, Lawrence A. Hansen, Eliezer Masliah and Fred H. Gage

Journal of Neuroscience 30 December 2016, 37 (7) 1675-1684; https://doi.org/10.1523/JNEUROSCI.3047-16.2016
Articles, Neurobiology of Disease
Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model
Brian Spencer, Paula A. Desplats, Cassia R. Overk, Elvira Valera-Martin, Robert A. Rissman, Chengbiao Wu, Michael Mante, Anthony Adame, Jazmin Florio, Edward Rockenstein and Eliezer Masliah

Journal of Neuroscience 27 July 2016, 36 (30) 7971-7984; https://doi.org/10.1523/JNEUROSCI.0775-16.2016
Articles, Neurobiology of Disease
Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons
Joseph R. Mazzulli, Friederike Zunke, Taiji Tsunemi, Nicholas J. Toker, Sohee Jeon, Lena F. Burbulla, Samarjit Patnaik, Ellen Sidransky, Juan J. Marugan, Carolyn M. Sue and Dimitri Krainc

Journal of Neuroscience 20 July 2016, 36 (29) 7693-7706; https://doi.org/10.1523/JNEUROSCI.0628-16.2016
Articles, Neurobiology of Disease
A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism
Elma Aflaki, Daniel K. Borger, Nima Moaven, Barbara K. Stubblefield, Steven A. Rogers, Samarjit Patnaik, Frank J. Schoenen, Wendy Westbroek, Wei Zheng, Patricia Sullivan, Hideji Fujiwara, Rohini Sidhu, Zayd M Khaliq, Grisel J. Lopez, David S. Goldstein, Daniel S. Ory, Juan Marugan and Ellen Sidransky

Journal of Neuroscience 13 July 2016, 36 (28) 7441-7452; https://doi.org/10.1523/JNEUROSCI.0636-16.2016
Articles, Neurobiology of Disease
Poststroke Induction of α-Synuclein Mediates Ischemic Brain Damage
TaeHee Kim, Suresh L. Mehta, Balarama Kaimal, Kirsten Lyons, Robert J. Dempsey and Raghu Vemuganti

Journal of Neuroscience 29 June 2016, 36 (26) 7055-7065; https://doi.org/10.1523/JNEUROSCI.1241-16.2016
Articles, Cellular/Molecular
Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration
Hongwei Qin, Jessica A. Buckley, Xinru Li, Yudong Liu, Thomas H. Fox, Gordon P. Meares, Hao Yu, Zhaoqi Yan, Ashley S. Harms, Yufeng Li, David G. Standaert and Etty N. Benveniste

Journal of Neuroscience 4 May 2016, 36 (18) 5144-5159; https://doi.org/10.1523/JNEUROSCI.4658-15.2016
Featured ArticleBrief Communications
α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals
Jianhua Xu, Xin-Sheng Wu, Jiansong Sheng, Zhen Zhang, Hai-Yuan Yue, Lixin Sun, Carmelo Sgobio, Xian Lin, Shiyong Peng, Yinghui Jin, Lin Gan, Huaibin Cai and Ling-Gang Wu

Journal of Neuroscience 20 April 2016, 36 (16) 4408-4414; https://doi.org/10.1523/JNEUROSCI.3627-15.2016
Brief Communications
microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease
Aaron D. Thome, Ashley S. Harms, Laura A. Volpicelli-Daley and David G. Standaert

Journal of Neuroscience 24 February 2016, 36 (8) 2383-2390; https://doi.org/10.1523/JNEUROSCI.3900-15.2016
Articles, Cellular/Molecular
VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease
Fu-Lei Tang, Joanna R. Erion, Yun Tian, Wei Liu, Dong-Min Yin, Jian Ye, Baisha Tang, Lin Mei and Wen-Cheng Xiong

Journal of Neuroscience 22 July 2015, 35 (29) 10613-10628; https://doi.org/10.1523/JNEUROSCI.0042-15.2015
Articles, Neurobiology of Disease
ATP13A2/PARK9 Regulates Secretion of Exosomes and α-Synuclein
Taiji Tsunemi, Kana Hamada and Dimitri Krainc

Journal of Neuroscience 12 November 2014, 34 (46) 15281-15287; https://doi.org/10.1523/JNEUROSCI.1629-14.2014

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