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Featured ArticleResearch Articles, Cellular/Molecular
Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99)
Ying Jiang, Yutaka Sato, Eunju Im, Martin Berg, Matteo Bordi, Sandipkumar Darji, Asok Kumar, Panaiyur S. Mohan, Urmi Bandyopadhyay, Antonio Diaz, Ana Maria Cuervo and Ralph A. Nixon

Journal of Neuroscience 1 May 2019, 39 (27) 5255-5268; DOI: https://doi.org/10.1523/JNEUROSCI.0578-19.2019
Research Articles, Neurobiology of Disease
Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome Pathway
Lisa P. Elia, Amanda R. Mason, Amela Alijagic and Steven Finkbeiner

Journal of Neuroscience 29 January 2019, 39 (17) 3332-3344; DOI: https://doi.org/10.1523/JNEUROSCI.3498-17.2019
Research Articles, Neurobiology of Disease
Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease
Taylor R. Jay, Anna M. Hirsch, Margaret L. Broihier, Crystal M. Miller, Lee E. Neilson, Richard M. Ransohoff, Bruce T. Lamb and Gary E. Landreth

Journal of Neuroscience 9 December 2016, 37 (3) 637-647; DOI: https://doi.org/10.1523/JNEUROSCI.2110-16.2016
Articles, Neurobiology of Disease
Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease
Antonella Caccamo, Caterina Branca, Joshua S. Talboom, Darren M. Shaw, Dharshaun Turner, Luyao Ma, Angela Messina, Zebing Huang, Jie Wu and Salvatore Oddo

Journal of Neuroscience 14 October 2015, 35 (41) 14042-14056; DOI: https://doi.org/10.1523/JNEUROSCI.2781-15.2015
Articles, Neurobiology of Disease
Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease
Andrea Megill, Trinh Tran, Kiara Eldred, Nathanael J. Lee, Philip C. Wong, Hyang-Sook Hoe, Alfredo Kirkwood and Hey-Kyoung Lee

Journal of Neuroscience 12 August 2015, 35 (32) 11346-11357; DOI: https://doi.org/10.1523/JNEUROSCI.5289-14.2015

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