alpha-synuclein

Research Articles, Neurobiology of Disease
Rab27b Promotes Lysosomal Function and Alpha-Synuclein Clearance in Neurons
Kasandra Scholz, Rudradip Pattanayak, Roschongporn Ekkatine, F. Sanders Pair, Amber Nobles, William J. Stone and Talene A. Yacoubian

Journal of Neuroscience 18 February 2025, 45 (14) e1579242025; https://doi.org/10.1523/JNEUROSCI.1579-24.2025
Research Articles, Neurobiology of Disease
Alpha-Synuclein Inhibits the Secretion of Extracellular Vesicles through Disruptions in YKT6 Lipidation
Taiji Tsunemi, Yuta Ishiguro, Asako Yoroisaka, Dou Feng, Tomoyo Shimada, Shunichi Niiyama, Yukiko Sasazawa, Keiichi Ishikawa, Wado Akamatsu and Nobutaka Hattori

Journal of Neuroscience 10 January 2025, 45 (11) e2350232024; https://doi.org/10.1523/JNEUROSCI.2350-23.2024
Featured ArticleResearch Articles, Neurobiology of Disease
Intracellular Accumulation of α-Synuclein Aggregates Promotes S-Nitrosylation of MAP1A Leading to Decreased NMDAR-Evoked Calcium Influx and Loss of Mature Synaptic Spines
Ryan D. Hallam, Brodie Buchner-Duby, Morgan G. Stykel, Carla L. Coackley and Scott D. Ryan

Journal of Neuroscience 22 November 2022, 42 (50) 9473-9487; https://doi.org/10.1523/JNEUROSCI.0074-22.2022
Featured ArticleResearch Articles, Neurobiology of Disease
REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model
Brent J. Ryan, Nora Bengoa-Vergniory, Matthew Williamson, Ecem Kirkiz, Rosalind Roberts, Gabriele Corda, Maximilian Sloan, Saba Saqlain, Marta Cherubini, Josse Poppinga, Helle Bogetofte, Milena Cioroch, Svenja Hester and Richard Wade-Martins

Journal of Neuroscience 9 February 2021, 41 (16) 3731-3746; https://doi.org/10.1523/JNEUROSCI.1478-20.2021
Research Articles, Neurobiology of Disease
4E-BP1 Protects Neurons from Misfolded Protein Stress and Parkinson's Disease Toxicity by Inducing the Mitochondrial Unfolded Protein Response
Somasish Ghosh Dastidar, Michael T. Pham, Matthew B. Mitchell, Steven G. Yeom, Sarah Jordan, Angela Chang, Bryce L. Sopher and Albert R. La Spada

Journal of Neuroscience 12 October 2020, 40 (45) 8734-8745; https://doi.org/10.1523/JNEUROSCI.0940-20.2020
Symposium and Mini-Symposium
New Frontiers in Parkinson's Disease: From Genetics to the Clinic
Lamya S. Shihabuddin, Patrik Brundin, J. Timothy Greenamyre, Diane Stephenson and S. Pablo Sardi

Journal of Neuroscience 31 October 2018, 38 (44) 9375-9382; https://doi.org/10.1523/JNEUROSCI.1666-18.2018
Cover ArticleResearch Articles, Neurobiology of Disease
Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
Jinar Rostami, Staffan Holmqvist, Veronica Lindström, Jessica Sigvardson, Gunilla T Westermark, Martin Ingelsson, Joakim Bergström, Laurent Roybon and Anna Erlandsson

Journal of Neuroscience 31 October 2017, 37 (49) 11835-11853; https://doi.org/10.1523/JNEUROSCI.0983-17.2017
Research Articles, Neurobiology of Disease
Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease
Bryan A. Martinez, Daniel A. Petersen, Anthony L. Gaeta, Samuel P. Stanley, Guy A. Caldwell and Kim A. Caldwell

Journal of Neuroscience 13 October 2017, 37 (46) 11085-11100; https://doi.org/10.1523/JNEUROSCI.1294-17.2017
Dual Perspectives
Parkinson's Disease Is Not Simply a Prion Disorder
D. James Surmeier, José A. Obeso and Glenda M. Halliday

Journal of Neuroscience 11 October 2017, 37 (41) 9799-9807; https://doi.org/10.1523/JNEUROSCI.1787-16.2017
Dual Perspectives
Prying into the Prion Hypothesis for Parkinson's Disease
Patrik Brundin and Ronald Melki

Journal of Neuroscience 11 October 2017, 37 (41) 9808-9818; https://doi.org/10.1523/JNEUROSCI.1788-16.2017

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