ALS

Featured ArticleResearch Articles, Cellular/Molecular
PolyQ-Expansion of Ataxin-2 Disrupts Microtubule Stability and Impairs Axon Outgrowth
Sun K. Kim and Vladimir I. Gelfand

Journal of Neuroscience 4 September 2025, 45 (40) e0682252025; https://doi.org/10.1523/JNEUROSCI.0682-25.2025
Cover ArticleFeatured ArticleResearch Articles, Neurobiology of Disease
ALS Mutations Shift the Isoelectric Point of the KIF5A C Terminal Inducing Protein Aggregation and TDP-43 Mislocalization
Pietro Zanella, Isabel Loss, Rosanna Parlato, Jochen H. Weishaupt, Carlo Sala, Chiara Verpelli, Tobias M. Boeckers and Alberto Catanese

Journal of Neuroscience 24 June 2025, 45 (31) e1658242025; https://doi.org/10.1523/JNEUROSCI.1658-24.2025
Cover ArticleResearch Articles, Neurobiology of Disease
C9ORF72 Deficiency Results in Neurodegeneration in the Zebrafish Retina
Natalia Jaroszynska, Andrea Salzinger, Themistoklis M. Tsarouchas, Catherina G. Becker, Thomas Becker, David A. Lyons, Ryan B. MacDonald and Marcus Keatinge

Journal of Neuroscience 24 April 2024, 44 (25) e2128232024; https://doi.org/10.1523/JNEUROSCI.2128-23.2024
Featured ArticleResearch Articles, Neurobiology of Disease
Loss of Activity-Induced Mitochondrial ATP Production Underlies the Synaptic Defects in a Drosophila Model of ALS
Nicholas E. Karagas, Richa Gupta, Elham Rastegari, Kai Li Tan, Ho Hang Leung, Hugo J. Bellen, Kartik Venkatachalam and Ching-On Wong

Journal of Neuroscience 8 September 2022, 42 (42) 8019-8037; https://doi.org/10.1523/JNEUROSCI.2456-21.2022
Symposium and Mini-Symposium
Phenotypic Suppression of ALS/FTD-Associated Neurodegeneration Highlights Mechanisms of Dysfunction
Mathieu Bartoletti, Daryl A. Bosco, Sandrine Da Cruz, Clotilde Lagier-Tourenne, Nicole Liachko, Sebastian Markmiller, Kristin M. Webster and Kristi A. Wharton

Journal of Neuroscience 16 October 2019, 39 (42) 8217-8224; https://doi.org/10.1523/JNEUROSCI.1159-19.2019
Featured ArticleResearch Articles, Neurobiology of Disease
Circuit Dysfunction in SOD1-ALS Model First Detected in Sensory Feedback Prior to Motor Neuron Degeneration Is Alleviated by BMP Signaling
Aaron Held, Paxton Major, Asli Sahin, Robert A. Reenan, Diane Lipscombe and Kristi A. Wharton

Journal of Neuroscience 18 January 2019, 39 (12) 2347-2364; https://doi.org/10.1523/JNEUROSCI.1771-18.2019
Research Articles, Neurobiology of Disease
C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in Drosophila Glutamatergic Neurons
Wangchao Xu and Jin Xu

Journal of Neuroscience 23 July 2018, 38 (35) 7741-7752; https://doi.org/10.1523/JNEUROSCI.0908-18.2018
Research Articles, Cellular/Molecular
miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non–Cell-Autonomous Mechanism in ALS
Roy Maimon, Ariel Ionescu, Avichai Bonnie, Sahar Sweetat, Shane Wald-Altman, Shani Inbar, Tal Gradus, Davide Trotti, Miguel Weil, Oded Behar and Eran Perlson

Journal of Neuroscience 17 May 2018, 38 (24) 5478-5494; https://doi.org/10.1523/JNEUROSCI.3037-17.2018
Research Articles, Neurobiology of Disease
Opposite Synaptic Alterations at the Neuromuscular Junction in an ALS Mouse Model: When Motor Units Matter
Elsa Tremblay, Éric Martineau and Richard Robitaille

Journal of Neuroscience 11 August 2017, 37 (37) 8901-8918; https://doi.org/10.1523/JNEUROSCI.3090-16.2017
Research Articles, Neurobiology of Disease
MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models
Mariah L. Hoye, Erica D. Koval, Amy J. Wegener, Theodore S. Hyman, Chengran Yang, David R. O'Brien, Rebecca L. Miller, Tracy Cole, Kathleen M. Schoch, Tao Shen, Tomonori Kunikata, Jean-Philippe Richard, David H. Gutmann, Nicholas J. Maragakis, Holly B. Kordasiewicz, Joseph D. Dougherty and Timothy M. Miller

Journal of Neuroscience 17 April 2017, 37 (22) 5574-5586; https://doi.org/10.1523/JNEUROSCI.3582-16.2017

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