Alzheimer's disease

Research Articles, Neurobiology of Disease
Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice
Agnieszka Staniszewski, Hong Zhang, Kesava Asam, Rose Pitstick, Michael P. Kavanaugh, Ottavio Arancio and Russell E. Nicholls

Journal of Neuroscience 27 April 2020, 40 (23) 4596-4608; https://doi.org/10.1523/JNEUROSCI.2983-19.2020
Research Articles, Neurobiology of Disease
Urokinase-Type Plasminogen Activator Protects Cerebral Cortical Neurons from Soluble Aβ-Induced Synaptic Damage
Ariel Diaz, Paola Merino, Ji-Dong Guo, Manuel A. Yepes, Patrick McCann, Tapasya Katta, Elise M. Tong, Enrique Torre, Srikant Rangaraju and Manuel Yepes

Journal of Neuroscience 24 April 2020, 40 (21) 4251-4263; https://doi.org/10.1523/JNEUROSCI.2804-19.2020
Research Articles, Neurobiology of Disease
Selective Disruption of Inhibitory Synapses Leading to Neuronal Hyperexcitability at an Early Stage of Tau Pathogenesis in a Mouse Model
Masafumi Shimojo, Hiroyuki Takuwa, Yuhei Takado, Masaki Tokunaga, Satoshi Tsukamoto, Keiichiro Minatohara, Maiko Ono, Chie Seki, Jun Maeda, Takuya Urushihata, Takeharu Minamihisamatsu, Ichio Aoki, Kazunori Kawamura, Ming-Rong Zhang, Tetsuya Suhara, Naruhiko Sahara and Makoto Higuchi

Journal of Neuroscience 7 April 2020, 40 (17) 3491-3501; https://doi.org/10.1523/JNEUROSCI.2880-19.2020
Cover ArticleResearch Articles, Neurobiology of Disease
Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
William J. Meilandt, Hai Ngu, Alvin Gogineni, Guita Lalehzadeh, Seung-Hye Lee, Karpagam Srinivasan, Jose Imperio, Tiffany Wu, Martin Weber, Agatha J. Kruse, Kimberly L. Stark, Pamela Chan, Mandy Kwong, Zora Modrusan, Brad A. Friedman, Justin Elstrott, Oded Foreman, Amy Easton, Morgan Sheng and David V. Hansen

Journal of Neuroscience 24 January 2020, 40 (9) 1956-1974; https://doi.org/10.1523/JNEUROSCI.1871-19.2019
Research Articles, Neurobiology of Disease
Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice
Konrad M. Ricke, Shelly A. Cruz, Zhaohong Qin, Kaveh Farrokhi, Fariba Sharmin, Li Zhang, Michael A. Zasloff, Alexandre F.R. Stewart and Hsiao-Huei Chen

Journal of Neuroscience 8 January 2020, 40 (7) 1581-1593; https://doi.org/10.1523/JNEUROSCI.2120-19.2019
Research Articles, Neurobiology of Disease
Activated CX3CL1/Smad2 Signals Prevent Neuronal Loss and Alzheimer's Tau Pathology-Mediated Cognitive Dysfunction
Qingyuan Fan, Wanxia He, Manoshi Gayen, Marc Robert Benoit, Xiaoyang Luo, Xiangyou Hu and Riqiang Yan

Journal of Neuroscience 10 December 2019, 40 (5) 1133-1144; https://doi.org/10.1523/JNEUROSCI.1333-19.2019
Featured ArticleResearch Articles, Neurobiology of Disease
ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes
Varun Rawat, Shaowei Wang, Jian Sima, Roni Bar, Ori Liraz, Usha Gundimeda, Trusha Parekh, Jamie Chan, Jan O. Johansson, Chongren Tang, Helena C. Chui, Michael G. Harrington, Daniel M. Michaelson and Hussein N. Yassine

Journal of Neuroscience 22 October 2019, 39 (48) 9611-9622; https://doi.org/10.1523/JNEUROSCI.1400-19.2019
Research Articles, Neurobiology of Disease
Tau Misfolding Efficiently Propagates between Individual Intact Hippocampal Neurons
Grace I. Hallinan, Mariana Vargas-Caballero, Jonathan West and Katrin Deinhardt

Journal of Neuroscience 28 October 2019, 39 (48) 9623-9632; https://doi.org/10.1523/JNEUROSCI.1590-19.2019
Research Articles, Neurobiology of Disease
Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease
Mona Lei, Jonathan D. Teo, Huitong Song, Holly P. McEwen, Jun Yup Lee, Timothy A. Couttas, Thomas Duncan, Rose Chesworth, Josefine Bertz, Magdalena Przybyla, Janet Van Eersel, Benjamin Heng, Gilles J. Guillemin, Lars M. Ittner, Thomas Fath, Brett Garner, Arne Ittner, Tim Karl and Anthony S. Don

Journal of Neuroscience 22 October 2019, 39 (48) 9645-9659; https://doi.org/10.1523/JNEUROSCI.0524-19.2019
Dual Perspectives
Extracellular Vesicles and Neurodegenerative Diseases
Andrew F. Hill

Journal of Neuroscience 20 November 2019, 39 (47) 9269-9273; https://doi.org/10.1523/JNEUROSCI.0147-18.2019

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