amyloid beta

Research Articles, Neurobiology of Disease
Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP
Zemin Wang, Rosemary J. Jackson, Wei Hong, Walter M. Taylor, Grant T. Corbett, Arturo Moreno, Wen Liu, Shaomin Li, Matthew P. Frosch, Inna Slutsky, Tracy L. Young-Pearse, Tara L. Spires-Jones and Dominic M. Walsh

Journal of Neuroscience 3 November 2017, 37 (49) 11947-11966; https://doi.org/10.1523/JNEUROSCI.2009-17.2017
Research Articles, Cellular/Molecular
Membrane-Associated Effects of Glucocorticoid on BACE1 Upregulation and Aβ Generation: Involvement of Lipid Raft-Mediated CREB Activation
Gee Euhn Choi, Sei-Jung Lee, Hyun Jik Lee, So Hee Ko, Chang Woo Chae and Ho Jae Han

Journal of Neuroscience 3 August 2017, 37 (35) 8459-8476; https://doi.org/10.1523/JNEUROSCI.0074-17.2017
Research Articles, Development/Plasticity/Repair
Amyloid-β Peptide Is Needed for cGMP-Induced Long-Term Potentiation and Memory
Agostino Palmeri, Roberta Ricciarelli, Walter Gulisano, Daniela Rivera, Claudia Rebosio, Elisa Calcagno, Maria Rosaria Tropea, Silvia Conti, Utpal Das, Subhojit Roy, Maria Adelaide Pronzato, Ottavio Arancio, Ernesto Fedele and Daniela Puzzo

Journal of Neuroscience 16 June 2017, 37 (29) 6926-6937; https://doi.org/10.1523/JNEUROSCI.3607-16.2017
Articles, Neurobiology of Disease
A Human Monoclonal IgG That Binds Aβ Assemblies and Diverse Amyloids Exhibits Anti-Amyloid Activities In Vitro and In Vivo
Yona Levites, Brian O'Nuallain, Rama Devudu Puligedda, Tomas Ondrejcak, Sharad P. Adekar, Cindy Chen, Pedro E. Cruz, Awilda M. Rosario, Sallie Macy, Alexandra J. Mably, Dominic M. Walsh, Ruben Vidal, Alan Solomon, Daniel Brown, Michael J. Rowan, Todd E. Golde and Scott K. Dessain

Journal of Neuroscience 22 April 2015, 35 (16) 6265-6276; https://doi.org/10.1523/JNEUROSCI.5109-14.2015
Articles, Neurobiology of Disease
The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans
Patrick C. May, Brian A. Willis, Stephen L. Lowe, Robert A. Dean, Scott A. Monk, Patrick J. Cocke, James E. Audia, Leonard N. Boggs, Anthony R. Borders, Richard A. Brier, David O. Calligaro, Theresa A. Day, Larry Ereshefsky, Jon A. Erickson, Hykop Gevorkyan, Celedon R. Gonzales, Douglas E. James, Stanford S. Jhee, Steven F. Komjathy, Linglin Li, Terry D. Lindstrom, Brian M. Mathes, Ferenc Martényi, Scott M. Sheehan, Stephanie L. Stout, David E. Timm, Grant M. Vaught, Brian M. Watson, Leonard L. Winneroski, Zhixiang Yang and Dustin J. Mergott

Journal of Neuroscience 21 January 2015, 35 (3) 1199-1210; https://doi.org/10.1523/JNEUROSCI.4129-14.2015
Articles, Cellular/Molecular
CNS Amyloid-β, Soluble APP-α and -β Kinetics during BACE Inhibition
Justyna A. Dobrowolska, Maria S. Michener, Guoxin Wu, Bruce W. Patterson, Robert Chott, Vitaliy Ovod, Yuriy Pyatkivskyy, Kristin R. Wildsmith, Tom Kasten, Parker Mathers, Mandy Dancho, Christina Lennox, Brad E. Smith, David Gilberto, Debra McLoughlin, Daniel J. Holder, Andrew W. Stamford, Kevin E. Yarasheski, Matthew E. Kennedy, Mary J. Savage and Randall J. Bateman

Journal of Neuroscience 11 June 2014, 34 (24) 8336-8346; https://doi.org/10.1523/JNEUROSCI.0540-14.2014
Featured ArticleArticles, Neurobiology of Disease
1α,25-Dihydroxyvitamin D₃ Reduces Cerebral Amyloid-β Accumulation and Improves Cognition in Mouse Models of Alzheimer's Disease
Matthew R. Durk, Kyung Han, Edwin C. Y. Chow, Rosemary Ahrens, Jeffrey T. Henderson, Paul E. Fraser and K. Sandy Pang

Journal of Neuroscience 21 May 2014, 34 (21) 7091-7101; https://doi.org/10.1523/JNEUROSCI.2711-13.2014

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amyloid beta