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amyloid precursor protein

  • Featured ArticleResearch Articles, Cellular/Molecular
    Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived Neurons
    Rodrigo S. Chaves, My Tran, Andrew R. Holder, Alexandra M. Balcer, Andrea M. Dickey, Elizabeth A. Roberts, Brian G. Bober, Edgar Gutierrez, Brian P. Head, Alex Groisman, Lawrence S.B. Goldstein, Angels Almenar-Queralt and Sameer B. Shah
    Journal of Neuroscience 18 October 2021, 41 (49) 10034-10053; DOI: https://doi.org/10.1523/JNEUROSCI.2553-20.2021
  • Research Articles, Neurobiology of Disease
    p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model
    Ramón Martínez-Mármol, Nika Mohannak, Lei Qian, Tong Wang, Rachel S. Gormal, Marc J. Ruitenberg, Bart Vanhaesebroeck, Elizabeth J. Coulson and Frédéric A. Meunier
    Journal of Neuroscience 30 July 2019, 39 (40) 7976-7991; DOI: https://doi.org/10.1523/JNEUROSCI.0674-19.2019
  • Research Articles, Neurobiology of Disease
    Neuromodulatory Action of Picomolar Extracellular Aβ42 Oligomers on Presynaptic and Postsynaptic Mechanisms Underlying Synaptic Function and Memory
    Walter Gulisano, Marcello Melone, Cristian Ripoli, Maria Rosaria Tropea, Domenica D. Li Puma, Salvatore Giunta, Sara Cocco, Daniele Marcotulli, Nicola Origlia, Agostino Palmeri, Ottavio Arancio, Fiorenzo Conti, Claudio Grassi and Daniela Puzzo
    Journal of Neuroscience 24 May 2019, 39 (30) 5986-6000; DOI: https://doi.org/10.1523/JNEUROSCI.0163-19.2019
  • Research Articles, Neurobiology of Disease
    Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP
    Zemin Wang, Rosemary J. Jackson, Wei Hong, Walter M. Taylor, Grant T. Corbett, Arturo Moreno, Wen Liu, Shaomin Li, Matthew P. Frosch, Inna Slutsky, Tracy L. Young-Pearse, Tara L. Spires-Jones and Dominic M. Walsh
    Journal of Neuroscience 3 November 2017, 37 (49) 11947-11966; DOI: https://doi.org/10.1523/JNEUROSCI.2009-17.2017
  • Cover ArticleResearch Articles, Cellular/Molecular
    Amyloid Precursor Protein in Drosophila Glia Regulates Sleep and Genes Involved in Glutamate Recycling
    Abud Jose Farca Luna, Magali Perier and Laurent Seugnet
    Journal of Neuroscience 17 March 2017, 37 (16) 4289-4300; DOI: https://doi.org/10.1523/JNEUROSCI.2826-16.2017
  • Articles, Neurobiology of Disease
    APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease
    Gunjan D. Manocha, Angela M. Floden, Keiko Rausch, Joshua A. Kulas, Brett A. McGregor, Lalida Rojanathammanee, Kelley R. Puig, Kendra L. Puig, Sanjib Karki, Michael R. Nichols, Diane C. Darland, James E. Porter and Colin K. Combs
    Journal of Neuroscience 10 August 2016, 36 (32) 8471-8486; DOI: https://doi.org/10.1523/JNEUROSCI.4654-15.2016
  • Featured ArticleArticles, Neurobiology of Disease
    Direct Transcriptional Effects of Apolipoprotein E
    Veena Theendakara, Clare A. Peters-Libeu, Patricia Spilman, Karen S. Poksay, Dale E. Bredesen and Rammohan V. Rao
    Journal of Neuroscience 20 January 2016, 36 (3) 685-700; DOI: https://doi.org/10.1523/JNEUROSCI.3562-15.2016
  • Featured ArticleArticles, Neurobiology of Disease
    The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior
    Maja Klevanski, Ulrike Herrmann, Sascha W. Weyer, Romain Fol, Nathalie Cartier, David P. Wolfer, John H. Caldwell, Martin Korte and Ulrike C. Müller
    Journal of Neuroscience 9 December 2015, 35 (49) 16018-16033; DOI: https://doi.org/10.1523/JNEUROSCI.2009-15.2015
  • Articles, Neurobiology of Disease
    Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis
    Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Danielle L. Tripoli, Leah Czerniewski, Andrea Ballabio, John R. Cirrito, Abhinav Diwan and Jin-Moo Lee
    Journal of Neuroscience 2 September 2015, 35 (35) 12137-12151; DOI: https://doi.org/10.1523/JNEUROSCI.0705-15.2015
  • Featured ArticleArticles, Neurobiology of Disease
    The Amyloid Precursor Protein Controls Adult Hippocampal Neurogenesis through GABAergic Interneurons
    Baiping Wang, Zilai Wang, Lu Sun, Li Yang, Hongmei Li, Allysa L. Cole, Jennifer Rodriguez-Rivera, Hui-Chen Lu and Hui Zheng
    Journal of Neuroscience 1 October 2014, 34 (40) 13314-13325; DOI: https://doi.org/10.1523/JNEUROSCI.2848-14.2014

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