amyloid precursor protein

Cover ArticleFeatured ArticleResearch Articles, Neurobiology of Disease
The Icelandic Mutation (APP-A673T) Is Protective against Amyloid Pathology In Vivo
Sho Shimohama, Ryo Fujioka, Naomi Mihira, Misaki Sekiguchi, Luca Sartori, Daisuke Joho, Takashi Saito, Takaomi C. Saido, Jin Nakahara, Tomohito Hino, Atsushi Hoshino and Hiroki Sasaguri

Journal of Neuroscience 4 November 2024, 44 (47) e0223242024; https://doi.org/10.1523/JNEUROSCI.0223-24.2024
Research Articles, Cellular/Molecular
The Amyloid Precursor Protein Regulates Synaptic Transmission at Medial Perforant Path Synapses
Maximilian Lenz, Amelie Eichler, Pia Kruse, Christos Galanis, Dimitrios Kleidonas, Geoffroy Andrieux, Melanie Boerries, Peter Jedlicka, Ulrike Müller, Thomas Deller and Andreas Vlachos

Journal of Neuroscience 27 June 2023, 43 (29) 5290-5304; https://doi.org/10.1523/JNEUROSCI.1824-22.2023
Research Articles, Cellular/Molecular
Neurexin-β Mediates the Synaptogenic Activity of Amyloid Precursor Protein
Vedrana Cvetkovska, Yuan Ge, Qin Xu, Shaokun Li, Peng Zhang and Ann Marie Craig

Journal of Neuroscience 19 October 2022, 42 (48) 8936-8947; https://doi.org/10.1523/JNEUROSCI.0511-21.2022
Featured ArticleResearch Articles, Neurobiology of Disease
Genetic Mapping of APP and Amyloid-β Biology Modulation by Trisomy 21
Paige Mumford, Justin Tosh, Silvia Anderle, Eleni Gkanatsiou Wikberg, Gloria Lau, Sue Noy, Karen Cleverley, Takashi Saito, Takaomi C. Saido, Eugene Yu, Gunnar Brinkmalm, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Victor Tybulewicz, Elizabeth M.C. Fisher and Frances K. Wiseman

Journal of Neuroscience 14 July 2022, 42 (33) 6453-6468; https://doi.org/10.1523/JNEUROSCI.0521-22.2022
Featured ArticleResearch Articles, Cellular/Molecular
Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived Neurons
Rodrigo S. Chaves, My Tran, Andrew R. Holder, Alexandra M. Balcer, Andrea M. Dickey, Elizabeth A. Roberts, Brian G. Bober, Edgar Gutierrez, Brian P. Head, Alex Groisman, Lawrence S.B. Goldstein, Angels Almenar-Queralt and Sameer B. Shah

Journal of Neuroscience 18 October 2021, 41 (49) 10034-10053; https://doi.org/10.1523/JNEUROSCI.2553-20.2021
Research Articles, Neurobiology of Disease
p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model
Ramón Martínez-Mármol, Nika Mohannak, Lei Qian, Tong Wang, Rachel S. Gormal, Marc J. Ruitenberg, Bart Vanhaesebroeck, Elizabeth J. Coulson and Frédéric A. Meunier

Journal of Neuroscience 30 July 2019, 39 (40) 7976-7991; https://doi.org/10.1523/JNEUROSCI.0674-19.2019
Research Articles, Neurobiology of Disease
Neuromodulatory Action of Picomolar Extracellular Aβ42 Oligomers on Presynaptic and Postsynaptic Mechanisms Underlying Synaptic Function and Memory
Walter Gulisano, Marcello Melone, Cristian Ripoli, Maria Rosaria Tropea, Domenica D. Li Puma, Salvatore Giunta, Sara Cocco, Daniele Marcotulli, Nicola Origlia, Agostino Palmeri, Ottavio Arancio, Fiorenzo Conti, Claudio Grassi and Daniela Puzzo

Journal of Neuroscience 24 May 2019, 39 (30) 5986-6000; https://doi.org/10.1523/JNEUROSCI.0163-19.2019
Research Articles, Neurobiology of Disease
Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP
Zemin Wang, Rosemary J. Jackson, Wei Hong, Walter M. Taylor, Grant T. Corbett, Arturo Moreno, Wen Liu, Shaomin Li, Matthew P. Frosch, Inna Slutsky, Tracy L. Young-Pearse, Tara L. Spires-Jones and Dominic M. Walsh

Journal of Neuroscience 3 November 2017, 37 (49) 11947-11966; https://doi.org/10.1523/JNEUROSCI.2009-17.2017
Cover ArticleResearch Articles, Cellular/Molecular
Amyloid Precursor Protein in Drosophila Glia Regulates Sleep and Genes Involved in Glutamate Recycling
Abud Jose Farca Luna, Magali Perier and Laurent Seugnet

Journal of Neuroscience 17 March 2017, 37 (16) 4289-4300; https://doi.org/10.1523/JNEUROSCI.2826-16.2017
Articles, Neurobiology of Disease
APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease
Gunjan D. Manocha, Angela M. Floden, Keiko Rausch, Joshua A. Kulas, Brett A. McGregor, Lalida Rojanathammanee, Kelley R. Puig, Kendra L. Puig, Sanjib Karki, Michael R. Nichols, Diane C. Darland, James E. Porter and Colin K. Combs

Journal of Neuroscience 10 August 2016, 36 (32) 8471-8486; https://doi.org/10.1523/JNEUROSCI.4654-15.2016

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