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amyloid precursor protein

  • Cover ArticleFeatured ArticleResearch Articles, Neurobiology of Disease
    The Icelandic Mutation (APP-A673T) Is Protective against Amyloid Pathology In Vivo
    Sho Shimohama, Ryo Fujioka, Naomi Mihira, Misaki Sekiguchi, Luca Sartori, Daisuke Joho, Takashi Saito, Takaomi C. Saido, Jin Nakahara, Tomohito Hino, Atsushi Hoshino and Hiroki Sasaguri
    Journal of Neuroscience 4 November 2024, 44 (47) e0223242024; https://doi.org/10.1523/JNEUROSCI.0223-24.2024
  • Research Articles, Cellular/Molecular
    The Amyloid Precursor Protein Regulates Synaptic Transmission at Medial Perforant Path Synapses
    Maximilian Lenz, Amelie Eichler, Pia Kruse, Christos Galanis, Dimitrios Kleidonas, Geoffroy Andrieux, Melanie Boerries, Peter Jedlicka, Ulrike Müller, Thomas Deller and Andreas Vlachos
    Journal of Neuroscience 27 June 2023, 43 (29) 5290-5304; https://doi.org/10.1523/JNEUROSCI.1824-22.2023
  • Research Articles, Cellular/Molecular
    Neurexin-β Mediates the Synaptogenic Activity of Amyloid Precursor Protein
    Vedrana Cvetkovska, Yuan Ge, Qin Xu, Shaokun Li, Peng Zhang and Ann Marie Craig
    Journal of Neuroscience 19 October 2022, 42 (48) 8936-8947; https://doi.org/10.1523/JNEUROSCI.0511-21.2022
  • Featured ArticleResearch Articles, Neurobiology of Disease
    Genetic Mapping of APP and Amyloid-β Biology Modulation by Trisomy 21
    Paige Mumford, Justin Tosh, Silvia Anderle, Eleni Gkanatsiou Wikberg, Gloria Lau, Sue Noy, Karen Cleverley, Takashi Saito, Takaomi C. Saido, Eugene Yu, Gunnar Brinkmalm, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Victor Tybulewicz, Elizabeth M.C. Fisher and Frances K. Wiseman
    Journal of Neuroscience 14 July 2022, 42 (33) 6453-6468; https://doi.org/10.1523/JNEUROSCI.0521-22.2022
  • Featured ArticleResearch Articles, Cellular/Molecular
    Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived Neurons
    Rodrigo S. Chaves, My Tran, Andrew R. Holder, Alexandra M. Balcer, Andrea M. Dickey, Elizabeth A. Roberts, Brian G. Bober, Edgar Gutierrez, Brian P. Head, Alex Groisman, Lawrence S.B. Goldstein, Angels Almenar-Queralt and Sameer B. Shah
    Journal of Neuroscience 18 October 2021, 41 (49) 10034-10053; https://doi.org/10.1523/JNEUROSCI.2553-20.2021
  • Research Articles, Neurobiology of Disease
    p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model
    Ramón Martínez-Mármol, Nika Mohannak, Lei Qian, Tong Wang, Rachel S. Gormal, Marc J. Ruitenberg, Bart Vanhaesebroeck, Elizabeth J. Coulson and Frédéric A. Meunier
    Journal of Neuroscience 30 July 2019, 39 (40) 7976-7991; https://doi.org/10.1523/JNEUROSCI.0674-19.2019
  • Research Articles, Neurobiology of Disease
    Neuromodulatory Action of Picomolar Extracellular Aβ42 Oligomers on Presynaptic and Postsynaptic Mechanisms Underlying Synaptic Function and Memory
    Walter Gulisano, Marcello Melone, Cristian Ripoli, Maria Rosaria Tropea, Domenica D. Li Puma, Salvatore Giunta, Sara Cocco, Daniele Marcotulli, Nicola Origlia, Agostino Palmeri, Ottavio Arancio, Fiorenzo Conti, Claudio Grassi and Daniela Puzzo
    Journal of Neuroscience 24 May 2019, 39 (30) 5986-6000; https://doi.org/10.1523/JNEUROSCI.0163-19.2019
  • Research Articles, Neurobiology of Disease
    Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP
    Zemin Wang, Rosemary J. Jackson, Wei Hong, Walter M. Taylor, Grant T. Corbett, Arturo Moreno, Wen Liu, Shaomin Li, Matthew P. Frosch, Inna Slutsky, Tracy L. Young-Pearse, Tara L. Spires-Jones and Dominic M. Walsh
    Journal of Neuroscience 3 November 2017, 37 (49) 11947-11966; https://doi.org/10.1523/JNEUROSCI.2009-17.2017
  • Cover ArticleResearch Articles, Cellular/Molecular
    Amyloid Precursor Protein in Drosophila Glia Regulates Sleep and Genes Involved in Glutamate Recycling
    Abud Jose Farca Luna, Magali Perier and Laurent Seugnet
    Journal of Neuroscience 17 March 2017, 37 (16) 4289-4300; https://doi.org/10.1523/JNEUROSCI.2826-16.2017
  • Articles, Neurobiology of Disease
    APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease
    Gunjan D. Manocha, Angela M. Floden, Keiko Rausch, Joshua A. Kulas, Brett A. McGregor, Lalida Rojanathammanee, Kelley R. Puig, Kendra L. Puig, Sanjib Karki, Michael R. Nichols, Diane C. Darland, James E. Porter and Colin K. Combs
    Journal of Neuroscience 10 August 2016, 36 (32) 8471-8486; https://doi.org/10.1523/JNEUROSCI.4654-15.2016

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