amyloid precursor protein

Behavioral/Systems/Cognitive
PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation
J. Grayson Richards, Guy A. Higgins, Abdel-Mouttalib Ouagazzal, Laurence Ozmen, James N. C. Kew, Bernd Bohrmann, Pari Malherbe, Manfred Brockhaus, Hansruedi Loetscher, Christian Czech, Gerda Huber, Horst Bluethmann, Helmut Jacobsen and John A. Kemp

Journal of Neuroscience 1 October 2003, 23 (26) 8989-9003; DOI: https://doi.org/10.1523/JNEUROSCI.23-26-08989.2003
Development/Plasticity/Repair
Analysis of Neurons Created from Wild-Type and Alzheimer's Mutation Knock-In Embryonic Stem Cells by a Highly Efficient Differentiation Protocol
Yoichiro Abe, Keisuke Kouyama, Taisuke Tomita, Yusuke Tomita, Norimitsu Ban, Mikiro Nawa, Masaaki Matsuoka, Takako Niikura, Sadakazu Aiso, Yoshiko Kita, Takeshi Iwatsubo and Ikuo Nishimoto

Journal of Neuroscience 17 September 2003, 23 (24) 8513-8525; DOI: https://doi.org/10.1523/JNEUROSCI.23-24-08513.2003
Behavioral/Systems/Cognitive
Age-Dependent Impairment of Somatosensory Response in the Amyloid Precursor Protein 23 Transgenic Mouse Model of Alzheimer's Disease
Thomas Mueggler, Diana Baumann, Martin Rausch, Matthias Staufenbiel and Markus Rudin

Journal of Neuroscience 10 September 2003, 23 (23) 8231-8236; DOI: https://doi.org/10.1523/JNEUROSCI.23-23-08231.2003
BRIEF COMMUNICATIONS
App Gene Dosage Modulates Endosomal Abnormalities of Alzheimer's Disease in a Segmental Trisomy 16 Mouse Model of Down Syndrome
Anne M. Cataldo, Suzana Petanceska, Corrinne M. Peterhoff, Nicole B. Terio, Charles J. Epstein, Angela Villar, Elaine J. Carlson, Matthias Staufenbiel and Ralph A. Nixon

Journal of Neuroscience 30 July 2003, 23 (17) 6788-6792; DOI: https://doi.org/10.1523/JNEUROSCI.23-17-06788.2003
Cellular/Molecular
DNA Synthesis and Neuronal Apoptosis Caused by Familial Alzheimer Disease Mutants of the Amyloid Precursor Protein Are Mediated by the p21 Activated Kinase PAK3
Donna L. McPhie, Robert Coopersmith, Andrew Hines-Peralta, Yuzhi Chen, Kathryn J. Ivins, Susan P. Manly, Michael R. Kozlowski, Kim A. Neve and Rachael L. Neve

Journal of Neuroscience 30 July 2003, 23 (17) 6914-6927; DOI: https://doi.org/10.1523/JNEUROSCI.23-17-06914.2003
ARTICLE, Cellular/Molecular
Evidence That Synaptically Released β-Amyloid Accumulates as Extracellular Deposits in the Hippocampus of Transgenic Mice
Orly Lazarov, Michael Lee, Daniel A. Peterson and Sangram S. Sisodia

Journal of Neuroscience 15 November 2002, 22 (22) 9785-9793; DOI: https://doi.org/10.1523/JNEUROSCI.22-22-09785.2002
ARTICLE, Cellular/Molecular
Increased Extracellular Amyloid Deposition and Neurodegeneration in Human Amyloid Precursor Protein Transgenic Mice Deficient in Receptor-Associated Protein
Emily Van Uden, Margaret Mallory, Isaac Veinbergs, Michael Alford, Edward Rockenstein and Eliezer Masliah

Journal of Neuroscience 1 November 2002, 22 (21) 9298-9304; DOI: https://doi.org/10.1523/JNEUROSCI.22-21-09298.2002
ARTICLE, Cellular/Molecular
Activation of c-Jun N-Terminal Kinase and p38 in an Alzheimer's Disease Model Is Associated with Amyloid Deposition
Mary J. Savage, Yin-Guo Lin, John R. Ciallella, Dorothy G. Flood and Richard W. Scott

Journal of Neuroscience 1 May 2002, 22 (9) 3376-3385; DOI: https://doi.org/10.1523/JNEUROSCI.22-09-03376.2002
ARTICLE, Cellular/Molecular
Demonstration by Fluorescence Resonance Energy Transfer of Two Sites of Interaction between the Low-Density Lipoprotein Receptor-Related Protein and the Amyloid Precursor Protein: Role of the Intracellular Adapter Protein Fe65
Ayae Kinoshita, Christa M. Whelan, Carolyn J. Smith, Irena Mikhailenko, G. William Rebeck, Dudley K. Strickland and Bradley T. Hyman

Journal of Neuroscience 1 November 2001, 21 (21) 8354-8361; DOI: https://doi.org/10.1523/JNEUROSCI.21-21-08354.2001
ARTICLE, Cellular/Molecular
c-Jun N-Terminal Kinase (JNK)-Interacting Protein-1b/Islet-Brain-1 Scaffolds Alzheimer's Amyloid Precursor Protein with JNK
Shuji Matsuda, Takashi Yasukawa, Yasuko Homma, Yuko Ito, Takako Niikura, Takako Hiraki, Shuichi Hirai, Shigeo Ohno, Yoshiko Kita, Masaoki Kawasumi, Keisuke Kouyama, Tokuo Yamamoto, John M. Kyriakis and Ikuo Nishimoto

Journal of Neuroscience 1 September 2001, 21 (17) 6597-6607; DOI: https://doi.org/10.1523/JNEUROSCI.21-17-06597.2001

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