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amyotrophic lateral sclerosis

  • Research Articles, Neurobiology of Disease
    Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure
    Changho Chun, Jung Hyun Lee, Mark Bothwell, Paul Nghiem, Alec S. T. Smith and David L. Mack
    Journal of Neuroscience 27 February 2024, 44 (16) e1787232024; https://doi.org/10.1523/JNEUROSCI.1787-23.2024
  • Research Articles, Neurobiology of Disease
    ALS-Associated KIF5A Mutation Causes Locomotor Deficits Associated with Cytoplasmic Inclusions, Alterations of Neuromuscular Junctions, and Motor Neuron Loss
    Laurent Soustelle, Franck Aimond, Cristina López-Andrés, Véronique Brugioti, Cédric Raoul and Sophie Layalle
    Journal of Neuroscience 25 September 2023, 43 (47) 8058-8072; https://doi.org/10.1523/JNEUROSCI.0562-23.2023
  • Featured ArticleResearch Articles, Neurobiology of Disease
    The SYNGAP1 3′UTR Variant in ALS Patients Causes Aberrant SYNGAP1 Splicing and Dendritic Spine Loss by Recruiting HNRNPK
    Satoshi Yokoi, Takuji Ito, Kentaro Sahashi, Masahiro Nakatochi, Ryoichi Nakamura, Genki Tohnai, Yusuke Fujioka, Shinsuke Ishigaki, Tsuyoshi Udagawa, Yuishin Izumi, Mitsuya Morita, Osamu Kano, Masaya Oda, Takefumi Sone, Hideyuki Okano, Naoki Atsuta, Masahisa Katsuno, Yohei Okada and Gen Sobue
    Journal of Neuroscience 19 October 2022, 42 (47) 8881-8896; https://doi.org/10.1523/JNEUROSCI.0455-22.2022
  • Research Articles, Neurobiology of Disease
    C-Boutons and Their Influence on Amyotrophic Lateral Sclerosis Disease Progression
    Tyler L. Wells, Jacob R. Myles and Turgay Akay
    Journal of Neuroscience 11 August 2021, 41 (38) 8088-8101; https://doi.org/10.1523/JNEUROSCI.0660-21.2021
  • Featured ArticleResearch Articles, Neurobiology of Disease
    Neutral Lipid Cacostasis Contributes to Disease Pathogenesis in Amyotrophic Lateral Sclerosis
    James C. Dodge, Elizabeth H. Jensen, Jinlong Yu, S. Pablo Sardi, Allison R. Bialas, Tatyana V. Taksir, Dinesh S. Bangari and Lamya S. Shihabuddin
    Journal of Neuroscience 13 October 2020, 40 (47) 9137-9147; https://doi.org/10.1523/JNEUROSCI.1388-20.2020
  • Research Articles, Neurobiology of Disease
    Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling
    Kallol Dutta, Sai Sampath Thammisetty, Hejer Boutej, Christine Bareil and Jean-Pierre Julien
    Journal of Neuroscience 26 May 2020, 40 (26) 5137-5154; https://doi.org/10.1523/JNEUROSCI.0536-20.2020
  • Research Articles, Neurobiology of Disease
    Circuit-Specific Early Impairment of Proprioceptive Sensory Neurons in the SOD1G93A Mouse Model for ALS
    Soju Seki, Toru Yamamoto, Kiara Quinn, Igor Spigelman, Antonios Pantazis, Riccardo Olcese, Martina Wiedau-Pazos, Scott H. Chandler and Sharmila Venugopal
    Journal of Neuroscience 17 September 2019, 39 (44) 8798-8815; https://doi.org/10.1523/JNEUROSCI.1214-19.2019
  • Research Articles, Neurobiology of Disease
    Restoration of Motor Defects Caused by Loss of Drosophila TDP-43 by Expression of the Voltage-Gated Calcium Channel, Cacophony, in Central Neurons
    Kayly M. Lembke, Charles Scudder and David B. Morton
    Journal of Neuroscience 28 August 2017, 37 (39) 9486-9497; https://doi.org/10.1523/JNEUROSCI.0554-17.2017
  • Research Articles, Neurobiology of Disease
    Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
    Laura Pasetto, Silvia Pozzi, Mariachiara Castelnovo, Manuela Basso, Alvaro G. Estevez, Stefano Fumagalli, Maria Grazia De Simoni, Valeria Castellaneta, Paolo Bigini, Elena Restelli, Roberto Chiesa, Francesca Trojsi, Maria Rosaria Monsurrò, Leonardo Callea, Miroslav Malešević, Gunter Fischer, Mattia Freschi, Massimo Tortarolo, Caterina Bendotti and Valentina Bonetto
    Journal of Neuroscience 23 December 2016, 37 (6) 1413-1427; https://doi.org/10.1523/JNEUROSCI.2462-16.2016
  • Articles, Neurobiology of Disease
    Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy
    Krista J. Spiller, Claudia J. Cheung, Clark R. Restrepo, Linda K. Kwong, Anna M. Stieber, John Q. Trojanowski and Virginia M.-Y. Lee
    Journal of Neuroscience 20 July 2016, 36 (29) 7707-7717; https://doi.org/10.1523/JNEUROSCI.1457-16.2016

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