apolipoprotein E

Featured ArticleResearch Articles, Neurobiology of Disease
Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis
Sadequl Islam, Yang Sun, Yuan Gao, Tomohisa Nakamura, Arshad Ali Noorani, Tong Li, Philip C. Wong, Noriyuki Kimura, Etsuro Matsubara, Kensaku Kasuga, Takeshi Ikeuchi, Taisuke Tomita, Kun Zou and Makoto Michikawa

Journal of Neuroscience 5 January 2022, 42 (8) 1574-1586; DOI: https://doi.org/10.1523/JNEUROSCI.2039-21.2021
Research Articles, Neurobiology of Disease
Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention
Long Wu, Xin Zhang and Liqin Zhao

Journal of Neuroscience 2 July 2018, 38 (30) 6665-6681; DOI: https://doi.org/10.1523/JNEUROSCI.2262-17.2018
Featured ArticleArticles, Neurobiology of Disease
Direct Transcriptional Effects of Apolipoprotein E
Veena Theendakara, Clare A. Peters-Libeu, Patricia Spilman, Karen S. Poksay, Dale E. Bredesen and Rammohan V. Rao

Journal of Neuroscience 20 January 2016, 36 (3) 685-700; DOI: https://doi.org/10.1523/JNEUROSCI.3562-15.2016
Articles, Neurobiology of Disease
APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration
Olivier Levy, Sophie Lavalette, Shulong J. Hu, Michael Housset, William Raoul, Chiara Eandi, José-Alain Sahel, Patrick M. Sullivan, Xavier Guillonneau and Florian Sennlaub

Journal of Neuroscience 7 October 2015, 35 (40) 13568-13576; DOI: https://doi.org/10.1523/JNEUROSCI.2468-15.2015
Articles, Neurobiology of Disease
Neuronal LRP1 Regulates Glucose Metabolism and Insulin Signaling in the Brain
Chia-Chen Liu, Jin Hu, Chih-Wei Tsai, Mei Yue, Heather L. Melrose, Takahisa Kanekiyo and Guojun Bu

Journal of Neuroscience 8 April 2015, 35 (14) 5851-5859; DOI: https://doi.org/10.1523/JNEUROSCI.5180-14.2015
Articles, Neurobiology of Disease
Anti-ApoE Antibody Given after Plaque Onset Decreases Aβ Accumulation and Improves Brain Function in a Mouse Model of Aβ Amyloidosis
Fan Liao, Yukiko Hori, Eloise Hudry, Adam Q. Bauer, Hong Jiang, Thomas E. Mahan, Katheryn B. Lefton, Tony J. Zhang, Joshua T. Dearborn, Jungsu Kim, Joseph P. Culver, Rebecca Betensky, David F. Wozniak, Bradley T. Hyman and David M. Holtzman

Journal of Neuroscience 21 May 2014, 34 (21) 7281-7292; DOI: https://doi.org/10.1523/JNEUROSCI.0646-14.2014
Development/Plasticity/Repair
Apolipoprotein E Markedly Facilitates Age-Dependent Cerebral Amyloid Angiopathy and Spontaneous Hemorrhage in Amyloid Precursor Protein Transgenic Mice
John D. Fryer, Jennie W. Taylor, Ronald B. DeMattos, Kelly R. Bales, Steven M. Paul, Maia Parsadanian and David M. Holtzman

Journal of Neuroscience 27 August 2003, 23 (21) 7889-7896; DOI: https://doi.org/10.1523/JNEUROSCI.23-21-07889.2003
ARTICLE, Cellular/Molecular
Modulation of Alzheimer-Like Synaptic and Cholinergic Deficits in Transgenic Mice by Human Apolipoprotein E Depends on Isoform , Aging, and Overexpression of Amyloid β Peptides But Not on Plaque Formation
Manuel Buttini, Gui-Qiu Yu, Kristina Shockley, Yadong Huang, Brian Jones, Eliezer Masliah, Margaret Mallory, Tracy Yeo, Frank M. Longo and Lennart Mucke

Journal of Neuroscience 15 December 2002, 22 (24) 10539-10548; DOI: https://doi.org/10.1523/JNEUROSCI.22-24-10539.2002
ARTICLE, Cellular/Molecular
Interactions between Apolipoprotein E Gene and Dietary α-Tocopherol Influence Cerebral Oxidative Damage in Aged Mice
Erin E. Reich, Kathleen S. Montine, Myron D. Gross, L. Jackson Roberts, Larry L. Swift, Jason D. Morrow and Thomas J. Montine

Journal of Neuroscience 15 August 2001, 21 (16) 5993-5999; DOI: https://doi.org/10.1523/JNEUROSCI.21-16-05993.2001
ARTICLE, Cellular/Molecular
Neuronal Apoptosis by Apolipoprotein E4 through Low-Density Lipoprotein Receptor-Related Protein and Heterotrimeric GTPases
Yuichi Hashimoto, Hong Jiang, Takako Niikura, Yuko Ito, Akari Hagiwara, Kazuo Umezawa, Yoichiro Abe, Yoshitake Murayama and Ikuo Nishimoto

Journal of Neuroscience 15 November 2000, 20 (22) 8401-8409; DOI: https://doi.org/10.1523/JNEUROSCI.20-22-08401.2000

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