APP

Featured ArticleResearch Articles, Neurobiology of Disease
Tuning of Glutamate, But Not GABA, Release by an Intrasynaptic Vesicle APP Domain Whose Function Can Be Modulated by β- or α-Secretase Cleavage
Wen Yao, Marc D. Tambini, Xinran Liu and Luciano D'Adamio

Journal of Neuroscience 24 June 2019, 39 (35) 6992-7005; DOI: https://doi.org/10.1523/JNEUROSCI.0207-19.2019
Cover ArticleResearch Articles, Neurobiology of Disease
BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism
Anna L. Stern, Shivesh Ghura, Patrick J. Gannon, Cagla Akay-Espinoza, Jessica M. Phan, Alan C. Yee, Robert Vassar, Benjamin B. Gelman, Dennis L. Kolson and Kelly L. Jordan-Sciutto

Journal of Neuroscience 9 April 2018, 38 (18) 4288-4300; DOI: https://doi.org/10.1523/JNEUROSCI.1280-17.2018
Research Articles, Neurobiology of Disease
Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome
Christopher M. William, Lubna Saqran, Matthew A. Stern, Charles L. Chiang, Scott P. Herrick, Aziz Rangwala, Mark W. Albers, Matthew P. Frosch and Bradley T. Hyman

Journal of Neuroscience 12 September 2017, 37 (41) 9880-9888; DOI: https://doi.org/10.1523/JNEUROSCI.1045-17.2017
Research Articles, Development/Plasticity/Repair
Amyloid-β Peptide Is Needed for cGMP-Induced Long-Term Potentiation and Memory
Agostino Palmeri, Roberta Ricciarelli, Walter Gulisano, Daniela Rivera, Claudia Rebosio, Elisa Calcagno, Maria Rosaria Tropea, Silvia Conti, Utpal Das, Subhojit Roy, Maria Adelaide Pronzato, Ottavio Arancio, Ernesto Fedele and Daniela Puzzo

Journal of Neuroscience 16 June 2017, 37 (29) 6926-6937; DOI: https://doi.org/10.1523/JNEUROSCI.3607-16.2017
Research Articles, Neurobiology of Disease
APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission
Sandra Schilling, Annika Mehr, Susann Ludewig, Jonathan Stephan, Marius Zimmermann, Alexander August, Paul Strecker, Martin Korte, Edward H. Koo, Ulrike C. Müller, Stefan Kins and Simone Eggert

Journal of Neuroscience 27 April 2017, 37 (21) 5345-5365; DOI: https://doi.org/10.1523/JNEUROSCI.1875-16.2017
Research Articles, Neurobiology of Disease
Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons
Valentina Lacovich, Sonia L. Espindola, Matías Alloatti, Victorio Pozo Devoto, Lucas E. Cromberg, Mária E. Čarná, Giancarlo Forte, Jean-Marc Gallo, Luciana Bruno, Gorazd B. Stokin, M. Elena Avale and Tomás L. Falzone

Journal of Neuroscience 11 November 2016, 37 (1) 58-69; DOI: https://doi.org/10.1523/JNEUROSCI.2305-16.2016
Articles, Neurobiology of Disease
Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels
Dimitri Hefter, Martin Kaiser, Sascha W. Weyer, Ismini E. Papageorgiou, Martin Both, Oliver Kann, Ulrike C. Müller and Andreas Draguhn

Journal of Neuroscience 10 August 2016, 36 (32) 8356-8371; DOI: https://doi.org/10.1523/JNEUROSCI.4130-15.2016
Articles, Neurobiology of Disease
SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein
Timothy Y. Huang, Yingjun Zhao, Xiaoguang Li, Xin Wang, I-Chu Tseng, Robert Thompson, Shichun Tu, Thomas E. Willnow, Yun-wu Zhang and Huaxi Xu

Journal of Neuroscience 27 July 2016, 36 (30) 7996-8011; DOI: https://doi.org/10.1523/JNEUROSCI.0206-16.2016
Articles, Neurobiology of Disease
ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology
Nobutaka Sakae, Chia-Chen Liu, Mitsuru Shinohara, Jessica Frisch-Daiello, Li Ma, Yu Yamazaki, Masaya Tachibana, Linda Younkin, Aishe Kurti, Minerva M. Carrasquillo, Fanggeng Zou, Daniel Sevlever, Gina Bisceglio, Ming Gan, Romain Fol, Patrick Knight, Miao Wang, Xianlin Han, John D. Fryer, Michael L. Fitzgerald, Yasumasa Ohyagi, Steven G. Younkin, Guojun Bu and Takahisa Kanekiyo

Journal of Neuroscience 30 March 2016, 36 (13) 3848-3859; DOI: https://doi.org/10.1523/JNEUROSCI.3757-15.2016
Articles, Neurobiology of Disease
Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes
Mei-Chen Liao, Christina R. Muratore, Todd M. Gierahn, Sarah E. Sullivan, Priya Srikanth, Philip L. De Jager, J. Christopher Love and Tracy L. Young-Pearse

Journal of Neuroscience 3 February 2016, 36 (5) 1730-1746; DOI: https://doi.org/10.1523/JNEUROSCI.2735-15.2016

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