APP

Featured ArticleResearch Articles, Neurobiology of Disease
Presenilin and APP Regulate Synaptic Kainate Receptors
Gaël Barthet, Ana Moreira-de-Sá, Pei Zhang, Séverine Deforges, Jorge Castanheira, Adam Gorlewicz and Christophe Mulle

Journal of Neuroscience 26 October 2022, 42 (49) 9253-9262; DOI: https://doi.org/10.1523/JNEUROSCI.0297-22.2022
Cover ArticleResearch Articles, Cellular/Molecular
APP Genetic Deficiency Alters Intracellular Ca²⁺ Homeostasis and Delays Axonal Degeneration in Dorsal Root Ganglion Sensory Neurons
Andrés de León, Julien Gibon and Philip A. Barker

Journal of Neuroscience 26 July 2022, 42 (35) 6680-6691; DOI: https://doi.org/10.1523/JNEUROSCI.0162-22.2022
Research Articles, Cellular/Molecular
DYRK1A Regulates the Bidirectional Axonal Transport of APP in Human-Derived Neurons
Iván Fernandez Bessone, Jordi Navarro, Emanuel Martinez, Karina Karmirian, Mariana Holubiec, Matias Alloatti, Livia Goto-Silva, Cayetana Arnaiz Yepez, Daniel Martins-de-Souza, Juliana Minardi Nascimento, Luciana Bruno, Trinidad M. Saez, Stevens K. Rehen and Tomás L. Falzone

Journal of Neuroscience 8 July 2022, 42 (33) 6344-6358; DOI: https://doi.org/10.1523/JNEUROSCI.2551-21.2022
Featured ArticleResearch Articles, Neurobiology of Disease
Tuning of Glutamate, But Not GABA, Release by an Intrasynaptic Vesicle APP Domain Whose Function Can Be Modulated by β- or α-Secretase Cleavage
Wen Yao, Marc D. Tambini, Xinran Liu and Luciano D'Adamio

Journal of Neuroscience 24 June 2019, 39 (35) 6992-7005; DOI: https://doi.org/10.1523/JNEUROSCI.0207-19.2019
Cover ArticleResearch Articles, Neurobiology of Disease
BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism
Anna L. Stern, Shivesh Ghura, Patrick J. Gannon, Cagla Akay-Espinoza, Jessica M. Phan, Alan C. Yee, Robert Vassar, Benjamin B. Gelman, Dennis L. Kolson and Kelly L. Jordan-Sciutto

Journal of Neuroscience 9 April 2018, 38 (18) 4288-4300; DOI: https://doi.org/10.1523/JNEUROSCI.1280-17.2018
Research Articles, Neurobiology of Disease
Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome
Christopher M. William, Lubna Saqran, Matthew A. Stern, Charles L. Chiang, Scott P. Herrick, Aziz Rangwala, Mark W. Albers, Matthew P. Frosch and Bradley T. Hyman

Journal of Neuroscience 12 September 2017, 37 (41) 9880-9888; DOI: https://doi.org/10.1523/JNEUROSCI.1045-17.2017
Research Articles, Development/Plasticity/Repair
Amyloid-β Peptide Is Needed for cGMP-Induced Long-Term Potentiation and Memory
Agostino Palmeri, Roberta Ricciarelli, Walter Gulisano, Daniela Rivera, Claudia Rebosio, Elisa Calcagno, Maria Rosaria Tropea, Silvia Conti, Utpal Das, Subhojit Roy, Maria Adelaide Pronzato, Ottavio Arancio, Ernesto Fedele and Daniela Puzzo

Journal of Neuroscience 16 June 2017, 37 (29) 6926-6937; DOI: https://doi.org/10.1523/JNEUROSCI.3607-16.2017
Research Articles, Neurobiology of Disease
APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission
Sandra Schilling, Annika Mehr, Susann Ludewig, Jonathan Stephan, Marius Zimmermann, Alexander August, Paul Strecker, Martin Korte, Edward H. Koo, Ulrike C. Müller, Stefan Kins and Simone Eggert

Journal of Neuroscience 27 April 2017, 37 (21) 5345-5365; DOI: https://doi.org/10.1523/JNEUROSCI.1875-16.2017
Research Articles, Neurobiology of Disease
Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons
Valentina Lacovich, Sonia L. Espindola, Matías Alloatti, Victorio Pozo Devoto, Lucas E. Cromberg, Mária E. Čarná, Giancarlo Forte, Jean-Marc Gallo, Luciana Bruno, Gorazd B. Stokin, M. Elena Avale and Tomás L. Falzone

Journal of Neuroscience 11 November 2016, 37 (1) 58-69; DOI: https://doi.org/10.1523/JNEUROSCI.2305-16.2016
Articles, Neurobiology of Disease
Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels
Dimitri Hefter, Martin Kaiser, Sascha W. Weyer, Ismini E. Papageorgiou, Martin Both, Oliver Kann, Ulrike C. Müller and Andreas Draguhn

Journal of Neuroscience 10 August 2016, 36 (32) 8356-8371; DOI: https://doi.org/10.1523/JNEUROSCI.4130-15.2016

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