cathepsin D

Featured ArticleResearch Articles, Cellular/Molecular
Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99)
Ying Jiang, Yutaka Sato, Eunju Im, Martin Berg, Matteo Bordi, Sandipkumar Darji, Asok Kumar, Panaiyur S. Mohan, Urmi Bandyopadhyay, Antonio Diaz, Ana Maria Cuervo and Ralph A. Nixon

Journal of Neuroscience 1 May 2019, 39 (27) 5255-5268; DOI: https://doi.org/10.1523/JNEUROSCI.0578-19.2019
Research Articles, Neurobiology of Disease
Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis
Andrew E. Arrant, Vincent C. Onyilo, Daniel E. Unger and Erik D. Roberson

Journal of Neuroscience 29 January 2018, 38 (9) 2341-2358; DOI: https://doi.org/10.1523/JNEUROSCI.3081-17.2018
ARTICLE, Cellular/Molecular
Huntingtin Expression Stimulates Endosomal–Lysosomal Activity, Endosome Tubulation, and Autophagy
Kimberly B. Kegel, Manho Kim, Ellen Sapp, Charmian McIntyre, José G. Castaño, Neil Aronin and Marian DiFiglia

Journal of Neuroscience 1 October 2000, 20 (19) 7268-7278; DOI: https://doi.org/10.1523/JNEUROSCI.20-19-07268.2000
ARTICLE, Cellular/Molecular
Cathepsin D Deficiency Induces Lysosomal Storage with Ceroid Lipofuscin in Mouse CNS Neurons
Masato Koike, Hiroshi Nakanishi, Paul Saftig, Junji Ezaki, Kyoko Isahara, Yoshiyuki Ohsawa, Walter Schulz-Schaeffer, Tsuyoshi Watanabe, Satoshi Waguri, Satoshi Kametaka, Masahiro Shibata, Kenji Yamamoto, Eiki Kominami, Christoph Peters, Kurt von Figura and Yasuo Uchiyama

Journal of Neuroscience 15 September 2000, 20 (18) 6898-6906; DOI: https://doi.org/10.1523/JNEUROSCI.20-18-06898.2000

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cathepsin D