gene therapy

Cover ArticleFeatured ArticleArticles, Development/Plasticity/Repair
Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury
Katalin Bartus, Nicholas D. James, Athanasios Didangelos, Karen D. Bosch, Joost Verhaagen, Rafael J. Yáñez-Muñoz, John H. Rogers, Bernard L. Schneider, Elizabeth M. Muir and Elizabeth J. Bradbury

Journal of Neuroscience 2 April 2014, 34 (14) 4822-4836; DOI: https://doi.org/10.1523/JNEUROSCI.4369-13.2014
Development/Plasticity/Repair
Ex Vivo Adenoviral Vector-Mediated Neurotrophin Gene Transfer to Olfactory Ensheathing Glia: Effects on Rubrospinal Tract Regeneration, Lesion Size, and Functional Recovery after Implantation in the Injured Rat Spinal Cord
Marc J. Ruitenberg, Giles W. Plant, Frank P. T. Hamers, Joke Wortel, Bas Blits, Paul A. Dijkhuizen, Willem Hendrik Gispen, Gerard J. Boer and Joost Verhaagen

Journal of Neuroscience 6 August 2003, 23 (18) 7045-7058; DOI: https://doi.org/10.1523/JNEUROSCI.23-18-07045.2003
BRIEF COMMUNICATIONS
Math1 Gene Transfer Generates New Cochlear Hair Cells in Mature Guinea Pigs In Vivo
Kohei Kawamoto, Shin-Ichi Ishimoto, Ryosei Minoda, Douglas E. Brough and Yehoash Raphael

Journal of Neuroscience 1 June 2003, 23 (11) 4395-4400; DOI: https://doi.org/10.1523/JNEUROSCI.23-11-04395.2003
ARTICLE, Development/Plasticity/Repair
Intravitreal Gene Therapy Reduces Lysosomal Storage in Specific Areas of the CNS in Mucopolysaccharidosis VII Mice
Anne K. Hennig, Beth Levy, Judith Mosinger Ogilvie, Carole A. Vogler, Nancy Galvin, Steven Bassnett and Mark S. Sands

Journal of Neuroscience 15 April 2003, 23 (8) 3302-3307; DOI: https://doi.org/10.1523/JNEUROSCI.23-08-03302.2003
BRIEF COMMUNICATION
Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice
Robert A. Marr, Edward Rockenstein, Atish Mukherjee, Mark S. Kindy, Louis B. Hersh, Fred H. Gage, Inder M. Verma and Eliezer Masliah

Journal of Neuroscience 15 March 2003, 23 (6) 1992-1996; DOI: https://doi.org/10.1523/JNEUROSCI.23-06-01992.2003
ARTICLE, Development/Plasticity/Repair
Multicistronic Lentiviral Vector-Mediated Striatal Gene Transfer of Aromatic l-Amino Acid Decarboxylase, Tyrosine Hydroxylase, and GTP Cyclohydrolase I Induces Sustained Transgene Expression, Dopamine Production, and Functional Improvement in a Rat Model of Parkinson's Disease.
Mimoun Azzouz, Enca Martin-Rendon, Robert D. Barber, Kyriacos A. Mitrophanous, Emma E. Carter, Jonathan B. Rohll, Susan M. Kingsman, Alan J. Kingsman and Nicholas D. Mazarakis

Journal of Neuroscience 1 December 2002, 22 (23) 10302-10312; DOI: https://doi.org/10.1523/JNEUROSCI.22-23-10302.2002
ARTICLE, Cellular/Molecular
Neuroprotective Effects of Glial Cell Line-Derived Neurotrophic Factor Mediated by an Adeno-Associated Virus Vector in a Transgenic Animal Model of Amyotrophic Lateral Sclerosis
Li-Jun Wang, Yan-Yan Lu, Shin-ichi Muramatsu, Kunihiko Ikeguchi, Ken-ichi Fujimoto, Takashi Okada, Hiroaki Mizukami, Takashi Matsushita, Yutaka Hanazono, Akihiro Kume, Toshiharu Nagatsu, Keiya Ozawa and Imaharu Nakano

Journal of Neuroscience 15 August 2002, 22 (16) 6920-6928; DOI: https://doi.org/10.1523/JNEUROSCI.22-16-06920.2002
ARTICLE, Cellular/Molecular
Distribution of a Lysosomal Enzyme in the Adult Brain by Axonal Transport and by Cells of the Rostral Migratory Stream
Marco A. Passini, Edward B. Lee, Gregory G. Heuer and John H. Wolfe

Journal of Neuroscience 1 August 2002, 22 (15) 6437-6446; DOI: https://doi.org/10.1523/JNEUROSCI.22-15-06437.2002
ARTICLE, Cellular/Molecular
Functional Regeneration of Chronically Injured Sensory Afferents into Adult Spinal Cord after Neurotrophin Gene Therapy
Mario I. Romero, Nagarathnamma Rangappa, Mary G. Garry and George M. Smith

Journal of Neuroscience 1 November 2001, 21 (21) 8408-8416; DOI: https://doi.org/10.1523/JNEUROSCI.21-21-08408.2001
ARTICLE, Development/Plasticity/Repair
Adenoviral Brain-Derived Neurotrophic Factor Induces Both Neostriatal and Olfactory Neuronal Recruitment from Endogenous Progenitor Cells in the Adult Forebrain
Abdellatif Benraiss, Eva Chmielnicki, Kim Lerner, Dongyon Roh and Steven A. Goldman

Journal of Neuroscience 1 September 2001, 21 (17) 6718-6731; DOI: https://doi.org/10.1523/JNEUROSCI.21-17-06718.2001

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