lysosome

Featured ArticleResearch Articles, Cellular/Molecular
Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99)
Ying Jiang, Yutaka Sato, Eunju Im, Martin Berg, Matteo Bordi, Sandipkumar Darji, Asok Kumar, Panaiyur S. Mohan, Urmi Bandyopadhyay, Antonio Diaz, Ana Maria Cuervo and Ralph A. Nixon

Journal of Neuroscience 1 May 2019, 39 (27) 5255-5268; DOI: https://doi.org/10.1523/JNEUROSCI.0578-19.2019
Research Articles, Neurobiology of Disease
Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome Pathway
Lisa P. Elia, Amanda R. Mason, Amela Alijagic and Steven Finkbeiner

Journal of Neuroscience 29 January 2019, 39 (17) 3332-3344; DOI: https://doi.org/10.1523/JNEUROSCI.3498-17.2019
Symposium and Mini-Symposium
The Endolysosomal System and Proteostasis: From Development to Degeneration
Bettina Winckler, Victor Faundez, Sandra Maday, Qian Cai, Cláudia Guimas Almeida and Huaye Zhang

Journal of Neuroscience 31 October 2018, 38 (44) 9364-9374; DOI: https://doi.org/10.1523/JNEUROSCI.1665-18.2018
Cover ArticleResearch Articles, Neurobiology of Disease
Codeficiency of Lysosomal Mucolipins 3 and 1 in Cochlear Hair Cells Diminishes Outer Hair Cell Longevity and Accelerates Age-Related Hearing Loss
Teerawat Wiwatpanit, Natalie N. Remis, Aisha Ahmad, Yingjie Zhou, John C. Clancy, Mary Ann Cheatham and Jaime García-Añoveros

Journal of Neuroscience 16 February 2018, 38 (13) 3177-3189; DOI: https://doi.org/10.1523/JNEUROSCI.3368-17.2018
Research Articles, Neurobiology of Disease
Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis
Andrew E. Arrant, Vincent C. Onyilo, Daniel E. Unger and Erik D. Roberson

Journal of Neuroscience 29 January 2018, 38 (9) 2341-2358; DOI: https://doi.org/10.1523/JNEUROSCI.3081-17.2018
Research Articles, Neurobiology of Disease
Mutant Huntingtin Is Secreted via a Late Endosomal/Lysosomal Unconventional Secretory Pathway
Katarina Trajkovic, Hyunkyung Jeong and Dimitri Krainc

Journal of Neuroscience 16 August 2017, 37 (37) 9000-9012; DOI: https://doi.org/10.1523/JNEUROSCI.0118-17.2017
Articles, Neurobiology of Disease
Reversal of Pathologic Lipid Accumulation in NPC1-Deficient Neurons by Drug-Promoted Release of LAMP1-Coated Lamellar Inclusions
Valérie Demais, Amélie Barthélémy, Martine Perraut, Nicole Ungerer, Céline Keime, Sophie Reibel and Frank W. Pfrieger

Journal of Neuroscience 27 July 2016, 36 (30) 8012-8025; DOI: https://doi.org/10.1523/JNEUROSCI.0900-16.2016
Articles, Neurobiology of Disease
Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis
Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Danielle L. Tripoli, Leah Czerniewski, Andrea Ballabio, John R. Cirrito, Abhinav Diwan and Jin-Moo Lee

Journal of Neuroscience 2 September 2015, 35 (35) 12137-12151; DOI: https://doi.org/10.1523/JNEUROSCI.0705-15.2015
Featured ArticleArticles, Cellular/Molecular
A Novel Size-Based Sorting Mechanism of Pinocytic Luminal Cargoes in Microglia
Cong Chen, Hui-Quan Li, Yi-jun Liu, Zhi-fei Guo, Hang-jun Wu, Xia Li, Hui-Fang Lou, Liya Zhu, Di Wang, Xiao-Ming Li, Li Yu, Xuetao Cao, Linrong Lu, Zhihua Gao and Shu-Min Duan

Journal of Neuroscience 11 February 2015, 35 (6) 2674-2688; DOI: https://doi.org/10.1523/JNEUROSCI.4389-14.2015
Cover ArticleArticles, Cellular/Molecular
Synaptic Strength Is Bidirectionally Controlled by Opposing Activity-Dependent Regulation of Nedd4-1 and USP8
Samantha L. Scudder, Marisa S. Goo, Anna E. Cartier, Alice Molteni, Lindsay A. Schwarz, Rebecca Wright and Gentry N. Patrick

Journal of Neuroscience 10 December 2014, 34 (50) 16637-16649; DOI: https://doi.org/10.1523/JNEUROSCI.2452-14.2014

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