mTOR

Research Articles, Neurobiology of Disease
mTORC2 Inhibition Improves Morphological Effects of PTEN Loss, But Does Not Correct Synaptic Dysfunction or Prevent Seizures
Erin R. Cullen, Kamran Tariq, Amy N. Shore, Bryan W. Luikart and Matthew C. Weston

Journal of Neuroscience 16 December 2022, 43 (5) 827-845; DOI: https://doi.org/10.1523/JNEUROSCI.1354-22.2022
Cover ArticleFeatured ArticleResearch Articles, Cellular/Molecular
Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the 5XFAD Alzheimer's Disease Model
Qian Shi, Cheng Chang, Afaf Saliba and Manzoor A. Bhat

Journal of Neuroscience 7 June 2022, 42 (27) 5294-5313; DOI: https://doi.org/10.1523/JNEUROSCI.2427-21.2022
Research Articles, Development/Plasticity/Repair
The Akt-mTOR Pathway Drives Myelin Sheath Growth by Regulating Cap-Dependent Translation
Karlie N. Fedder-Semmes and Bruce Appel

Journal of Neuroscience 2 September 2021, 41 (41) 8532-8544; DOI: https://doi.org/10.1523/JNEUROSCI.0783-21.2021
Research Articles, Development/Plasticity/Repair
mTOR Signaling Regulates Metabolic Function in Oligodendrocyte Precursor Cells and Promotes Efficient Brain Remyelination in the Cuprizone Model
Marisa A. Jeffries, Lauren E. McLane, Luipa Khandker, Marie L. Mather, Angelina V. Evangelou, Divyangi Kantak, Jennifer N. Bourne, Wendy B. Macklin and Teresa L. Wood

Journal of Neuroscience 20 August 2021, 41 (40) 8321-8337; DOI: https://doi.org/10.1523/JNEUROSCI.1377-20.2021
Research Articles, Cellular/Molecular
Tuberous Sclerosis Complex (TSC) Inactivation Increases Neuronal Network Activity by Enhancing Ca²⁺ Influx via L-Type Ca²⁺ Channels
Chihiro Hisatsune, Tadayuki Shimada, Akitoshi Miyamoto, Amy Lee and Kanato Yamagata

Journal of Neuroscience 20 August 2021, 41 (39) 8134-8149; DOI: https://doi.org/10.1523/JNEUROSCI.1930-20.2021
Viewpoints
SARS-CoV-2 Neuronal Invasion and Complications: Potential Mechanisms and Therapeutic Approaches
Olivia Swain, Sofia K. Romano, Ritika Miryala, Jocelyn Tsai, Vinnie Parikh and George K. E. Umanah

Journal of Neuroscience 23 June 2021, 41 (25) 5338-5349; DOI: https://doi.org/10.1523/JNEUROSCI.3188-20.2021
Featured ArticleResearch Articles, Neurobiology of Disease
mTOR Attenuation with Rapamycin Reverses Neurovascular Uncoupling and Memory Deficits in Mice Modeling Alzheimer's Disease
Candice E. Van Skike, Stacy A. Hussong, Stephen F. Hernandez, Andy Q. Banh, Nicholas DeRosa and Veronica Galvan

Journal of Neuroscience 22 April 2021, 41 (19) 4305-4320; DOI: https://doi.org/10.1523/JNEUROSCI.2144-20.2021
Research Articles, Cellular/Molecular
Microglial mTOR is Neuronal Protective and Antiepileptogenic in the Pilocarpine Model of Temporal Lobe Epilepsy
Xiao-Feng Zhao, Yuan Liao, Mahabub Maraj Alam, Ramkumar Mathur, Paul Feustel, Joseph E. Mazurkiewicz, Matthew A. Adamo, Xinjun C. Zhu and Yunfei Huang

Journal of Neuroscience 31 August 2020, 40 (40) 7593-7608; DOI: https://doi.org/10.1523/JNEUROSCI.2754-19.2020
Research Articles, Development/Plasticity/Repair
Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination
Aminat S. Musah, Tanya L. Brown, Marisa A. Jeffries, Quan Shang, Hirokazu Hashimoto, Angelina V. Evangelou, Alison Kowalski, Mona Batish, Wendy B. Macklin and Teresa L. Wood

Journal of Neuroscience 5 March 2020, 40 (15) 2993-3007; DOI: https://doi.org/10.1523/JNEUROSCI.1434-18.2020
Research Articles, Cellular/Molecular
Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons
Kellen D. Winden, Maria Sundberg, Cindy Yang, Syed M.A. Wafa, Sean Dwyer, Pin-Fang Chen, Elizabeth D. Buttermore and Mustafa Sahin

Journal of Neuroscience 7 October 2019, 39 (47) 9294-9305; DOI: https://doi.org/10.1523/JNEUROSCI.0642-19.2019

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