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mTOR

  • Research Articles, Neurobiology of Disease
    mTORC2 Inhibition Improves Morphological Effects of PTEN Loss, But Does Not Correct Synaptic Dysfunction or Prevent Seizures
    Erin R. Cullen, Kamran Tariq, Amy N. Shore, Bryan W. Luikart and Matthew C. Weston
    Journal of Neuroscience 16 December 2022, 43 (5) 827-845; DOI: https://doi.org/10.1523/JNEUROSCI.1354-22.2022
  • Cover ArticleFeatured ArticleResearch Articles, Cellular/Molecular
    Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the 5XFAD Alzheimer's Disease Model
    Qian Shi, Cheng Chang, Afaf Saliba and Manzoor A. Bhat
    Journal of Neuroscience 7 June 2022, 42 (27) 5294-5313; DOI: https://doi.org/10.1523/JNEUROSCI.2427-21.2022
  • Research Articles, Development/Plasticity/Repair
    The Akt-mTOR Pathway Drives Myelin Sheath Growth by Regulating Cap-Dependent Translation
    Karlie N. Fedder-Semmes and Bruce Appel
    Journal of Neuroscience 2 September 2021, 41 (41) 8532-8544; DOI: https://doi.org/10.1523/JNEUROSCI.0783-21.2021
  • Research Articles, Development/Plasticity/Repair
    mTOR Signaling Regulates Metabolic Function in Oligodendrocyte Precursor Cells and Promotes Efficient Brain Remyelination in the Cuprizone Model
    Marisa A. Jeffries, Lauren E. McLane, Luipa Khandker, Marie L. Mather, Angelina V. Evangelou, Divyangi Kantak, Jennifer N. Bourne, Wendy B. Macklin and Teresa L. Wood
    Journal of Neuroscience 20 August 2021, 41 (40) 8321-8337; DOI: https://doi.org/10.1523/JNEUROSCI.1377-20.2021
  • Research Articles, Cellular/Molecular
    Tuberous Sclerosis Complex (TSC) Inactivation Increases Neuronal Network Activity by Enhancing Ca2+ Influx via L-Type Ca2+ Channels
    Chihiro Hisatsune, Tadayuki Shimada, Akitoshi Miyamoto, Amy Lee and Kanato Yamagata
    Journal of Neuroscience 20 August 2021, 41 (39) 8134-8149; DOI: https://doi.org/10.1523/JNEUROSCI.1930-20.2021
  • Viewpoints
    SARS-CoV-2 Neuronal Invasion and Complications: Potential Mechanisms and Therapeutic Approaches
    Olivia Swain, Sofia K. Romano, Ritika Miryala, Jocelyn Tsai, Vinnie Parikh and George K. E. Umanah
    Journal of Neuroscience 23 June 2021, 41 (25) 5338-5349; DOI: https://doi.org/10.1523/JNEUROSCI.3188-20.2021
  • Featured ArticleResearch Articles, Neurobiology of Disease
    mTOR Attenuation with Rapamycin Reverses Neurovascular Uncoupling and Memory Deficits in Mice Modeling Alzheimer's Disease
    Candice E. Van Skike, Stacy A. Hussong, Stephen F. Hernandez, Andy Q. Banh, Nicholas DeRosa and Veronica Galvan
    Journal of Neuroscience 22 April 2021, 41 (19) 4305-4320; DOI: https://doi.org/10.1523/JNEUROSCI.2144-20.2021
  • Research Articles, Cellular/Molecular
    Microglial mTOR is Neuronal Protective and Antiepileptogenic in the Pilocarpine Model of Temporal Lobe Epilepsy
    Xiao-Feng Zhao, Yuan Liao, Mahabub Maraj Alam, Ramkumar Mathur, Paul Feustel, Joseph E. Mazurkiewicz, Matthew A. Adamo, Xinjun C. Zhu and Yunfei Huang
    Journal of Neuroscience 31 August 2020, 40 (40) 7593-7608; DOI: https://doi.org/10.1523/JNEUROSCI.2754-19.2020
  • Research Articles, Development/Plasticity/Repair
    Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination
    Aminat S. Musah, Tanya L. Brown, Marisa A. Jeffries, Quan Shang, Hirokazu Hashimoto, Angelina V. Evangelou, Alison Kowalski, Mona Batish, Wendy B. Macklin and Teresa L. Wood
    Journal of Neuroscience 5 March 2020, 40 (15) 2993-3007; DOI: https://doi.org/10.1523/JNEUROSCI.1434-18.2020
  • Research Articles, Cellular/Molecular
    Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons
    Kellen D. Winden, Maria Sundberg, Cindy Yang, Syed M.A. Wafa, Sean Dwyer, Pin-Fang Chen, Elizabeth D. Buttermore and Mustafa Sahin
    Journal of Neuroscience 7 October 2019, 39 (47) 9294-9305; DOI: https://doi.org/10.1523/JNEUROSCI.0642-19.2019

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