presenilin

Featured ArticleResearch Articles, Neurobiology of Disease
Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis
Sadequl Islam, Yang Sun, Yuan Gao, Tomohisa Nakamura, Arshad Ali Noorani, Tong Li, Philip C. Wong, Noriyuki Kimura, Etsuro Matsubara, Kensaku Kasuga, Takeshi Ikeuchi, Taisuke Tomita, Kun Zou and Makoto Michikawa

Journal of Neuroscience 5 January 2022, 42 (8) 1574-1586; DOI: https://doi.org/10.1523/JNEUROSCI.2039-21.2021
Featured ArticleResearch Articles, Neurobiology of Disease
Deficits in Enrichment-Dependent Neurogenesis and Enhanced Anxiety Behaviors Mediated by Expression of Alzheimer's Disease-Linked Ps1 Variants Are Rescued by Microglial Depletion
Sylvia Ortega-Martinez, Nisha Palla, Xiaoqiong Zhang, Erin Lipman and Sangram S. Sisodia

Journal of Neuroscience 19 June 2019, 39 (34) 6766-6780; DOI: https://doi.org/10.1523/JNEUROSCI.0884-19.2019
Brief Communications
Age-Dependent, Non-Cell-Autonomous Deposition of Amyloid from Synthesis of β-Amyloid by Cells Other Than Excitatory Neurons
Karthikeyan Veeraraghavalu, Can Zhang, Xiaoqiong Zhang, Rudolph E. Tanzi and Sangram S. Sisodia

Journal of Neuroscience 5 March 2014, 34 (10) 3668-3673; DOI: https://doi.org/10.1523/JNEUROSCI.5079-13.2014
Cellular/Molecular
Altered Aβ Formation and Long-Term Potentiation in a Calsenilin Knock-Out
Christina Lilliehook, Ozlem Bozdagi, Jun Yao, Manuel Gomez-Ramirez, Nikhat F. Zaidi, Wilma Wasco, Sam Gandy, Anthony C. Santucci, Vahram Haroutunian, George W. Huntley and Joseph D. Buxbaum

Journal of Neuroscience 8 October 2003, 23 (27) 9097-9106; DOI: https://doi.org/10.1523/JNEUROSCI.23-27-09097.2003
Cellular/Molecular
Presenilin Redistribution Associated with Aberrant Cholesterol Transport Enhances β-Amyloid Production In Vivo
Mark Burns, Kate Gaynor, Vicki Olm, Marc Mercken, John LaFrancois, Lili Wang, Paul M. Mathews, Wendy Noble, Yasuji Matsuoka and Karen Duff

Journal of Neuroscience 2 July 2003, 23 (13) 5645-5649; DOI: https://doi.org/10.1523/JNEUROSCI.23-13-05645.2003
Cellular/Molecular
Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport
Gustavo Pigino, Gerardo Morfini, Alejandra Pelsman, Mark P. Mattson, Scott T. Brady and Jorge Busciglio

Journal of Neuroscience 1 June 2003, 23 (11) 4499-4508; DOI: https://doi.org/10.1523/JNEUROSCI.23-11-04499.2003
Cellular/Molecular
Amyloid Precursor Protein Associates with a Nicastrin-Dependent Docking Site on the Presenilin 1–γ-Secretase Complex in Cells Demonstrated by Fluorescence Lifetime Imaging
Oksana Berezovska, Pavan Ramdya, Jesse Skoch, Michael S. Wolfe, Brian J. Bacskai and Bradley T. Hyman

Journal of Neuroscience 1 June 2003, 23 (11) 4560-4566; DOI: https://doi.org/10.1523/JNEUROSCI.23-11-04560.2003
ARTICLE, Cellular/Molecular
Activation of c-Jun N-Terminal Kinase and p38 in an Alzheimer's Disease Model Is Associated with Amyloid Deposition
Mary J. Savage, Yin-Guo Lin, John R. Ciallella, Dorothy G. Flood and Richard W. Scott

Journal of Neuroscience 1 May 2002, 22 (9) 3376-3385; DOI: https://doi.org/10.1523/JNEUROSCI.22-09-03376.2002
ARTICLE, Cellular/Molecular
Inhibition of Intracellular Cholesterol Transport Alters Presenilin Localization and Amyloid Precursor Protein Processing in Neuronal Cells
Heiko Runz, Jens Rietdorf, Inge Tomic, Marina de Bernard, Konrad Beyreuther, Rainer Pepperkok and Tobias Hartmann

Journal of Neuroscience 1 March 2002, 22 (5) 1679-1689; DOI: https://doi.org/10.1523/JNEUROSCI.22-05-01679.2002
ARTICLE, Cellular/Molecular
Presenilin-1 Mutations Reduce Cytoskeletal Association, Deregulate Neurite Growth, and Potentiate Neuronal Dystrophy and Tau Phosphorylation
Gustavo Pigino, Alejandra Pelsman, Hiroshi Mori and Jorge Busciglio

Journal of Neuroscience 1 February 2001, 21 (3) 834-842; DOI: https://doi.org/10.1523/JNEUROSCI.21-03-00834.2001

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