protease

Research Articles, Neurobiology of Disease
GPR120 Signaling Controls Amyloid-β Degrading Activity of Matrix Metalloproteinases
Kazunori Kikuchi, Takuya Tatebe, Yuki Sudo, Miyabishara Yokoyama, Kiwami Kidana, Yung Wen Chiu, Sho Takatori, Makoto Arita, Yukiko Hori and Taisuke Tomita

Journal of Neuroscience 7 June 2021, 41 (28) 6173-6185; DOI: https://doi.org/10.1523/JNEUROSCI.2595-20.2021
Featured ArticleResearch Articles, Neurobiology of Disease
Legumain Induces Oral Cancer Pain by Biased Agonism of Protease-Activated Receptor-2
Nguyen Huu Tu, Dane D. Jensen, Bethany M. Anderson, Elyssa Chen, Nestor N. Jimenez-Vargas, Nicole N. Scheff, Kenji Inoue, Hung D. Tran, John C. Dolan, Tamaryn A. Meek, Morley D. Hollenberg, Cheng Z. Liu, Stephen J. Vanner, Malvin N. Janal, Nigel W. Bunnett, Laura E. Edgington-Mitchell and Brian L. Schmidt

Journal of Neuroscience 10 November 2020, 41 (1) 193-210; DOI: https://doi.org/10.1523/JNEUROSCI.1211-20.2020
Research Articles, Cellular/Molecular
Modulation of Receptor Protein Tyrosine Phosphatase Sigma Increases Chondroitin Sulfate Proteoglycan Degradation through Cathepsin B Secretion to Enhance Axon Outgrowth
Amanda Phuong Tran, Sapna Sundar, Meigen Yu, Bradley T. Lang and Jerry Silver

Journal of Neuroscience 14 May 2018, 38 (23) 5399-5414; DOI: https://doi.org/10.1523/JNEUROSCI.3214-17.2018
Research Articles, Neurobiology of Disease
Activation of γ-Secretase Trimming Activity by Topological Changes of Transmembrane Domain 1 of Presenilin 1
Tetsuo Cai, Masahiro Yonaga and Taisuke Tomita

Journal of Neuroscience 8 November 2017, 37 (50) 12272-12280; DOI: https://doi.org/10.1523/JNEUROSCI.1628-17.2017
Research Articles, Cellular/Molecular
Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin
Himari Ogino, Arisa Hisanaga, Takao Kohno, Yuta Kondo, Kyoko Okumura, Takana Kamei, Tempei Sato, Hiroshi Asahara, Hitomi Tsuiji, Masaki Fukata and Mitsuharu Hattori

Journal of Neuroscience 17 February 2017, 37 (12) 3181-3191; DOI: https://doi.org/10.1523/JNEUROSCI.3632-16.2017
Articles, Neurobiology of Disease
Conformational Changes in Transmembrane Domain 4 of Presenilin 1 Are Associated with Altered Amyloid-β 42 Production
Aya Tominaga, Tetsuo Cai, Shizuka Takagi-Niidome, Takeshi Iwatsubo and Taisuke Tomita

Journal of Neuroscience 27 January 2016, 36 (4) 1362-1372; DOI: https://doi.org/10.1523/JNEUROSCI.5090-14.2016
Articles, Cellular/Molecular
Cooperative Roles of Hydrophilic Loop 1 and the C-Terminus of Presenilin 1 in the Substrate-Gating Mechanism of γ-Secretase
Shizuka Takagi-Niidome, Tomoki Sasaki, Satoko Osawa, Takeshi Sato, Kanan Morishima, Tetsuo Cai, Takeshi Iwatsubo and Taisuke Tomita

Journal of Neuroscience 11 February 2015, 35 (6) 2646-2656; DOI: https://doi.org/10.1523/JNEUROSCI.3164-14.2015
Cellular/Molecular
Selective Activation Induced Cleavage of the NR2B Subunit by Calpain
Kelly L. Simpkins, Rodney P. Guttmann, Yina Dong, Zhaoming Chen, Set Sokol, Robert W. Neumar and David R. Lynch

Journal of Neuroscience 12 December 2003, 23 (36) 11322-11331; DOI: https://doi.org/10.1523/JNEUROSCI.23-36-11322.2003
BRIEF COMMUNICATIONS
The Tissue Plasminogen Activator-Plasminogen Proteolytic Cascade Accelerates Amyloid-β (Aβ) Degradation and Inhibits Aβ-Induced Neurodegeneration
Jerry P. Melchor, Robert Pawlak and Sidney Strickland

Journal of Neuroscience 1 October 2003, 23 (26) 8867-8871; DOI: https://doi.org/10.1523/JNEUROSCI.23-26-08867.2003
Cellular/Molecular
Inhibition of Calpains Prevents Neuronal and Behavioral Deficits in an MPTP Mouse Model of Parkinson's Disease
Stephen J. Crocker, Patrice D. Smith, Vernice Jackson-Lewis, Wiplore R. Lamba, Shawn P. Hayley, Erich Grimm, Steve M. Callaghan, Ruth S. Slack, Edon Melloni, Serge Przedborski, George S. Robertson, Hymie Anisman, Zul Merali and David S. Park

Journal of Neuroscience 15 May 2003, 23 (10) 4081-4091; DOI: https://doi.org/10.1523/JNEUROSCI.23-10-04081.2003

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