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trem2

  • Cover ArticleFeatured ArticleResearch Articles, Cellular/Molecular
    Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the 5XFAD Alzheimer's Disease Model
    Qian Shi, Cheng Chang, Afaf Saliba and Manzoor A. Bhat
    Journal of Neuroscience 7 June 2022, 42 (27) 5294-5313; DOI: https://doi.org/10.1523/JNEUROSCI.2427-21.2022
  • Research Articles, Cellular/Molecular
    Loss of TREM2 Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice
    Wenhui Qu and Ling Li
    Journal of Neuroscience 2 November 2020, 40 (50) 9552-9563; DOI: https://doi.org/10.1523/JNEUROSCI.2193-20.2020
  • Cover ArticleResearch Articles, Neurobiology of Disease
    Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
    William J. Meilandt, Hai Ngu, Alvin Gogineni, Guita Lalehzadeh, Seung-Hye Lee, Karpagam Srinivasan, Jose Imperio, Tiffany Wu, Martin Weber, Agatha J. Kruse, Kimberly L. Stark, Pamela Chan, Mandy Kwong, Zora Modrusan, Brad A. Friedman, Justin Elstrott, Oded Foreman, Amy Easton, Morgan Sheng and David V. Hansen
    Journal of Neuroscience 24 January 2020, 40 (9) 1956-1974; DOI: https://doi.org/10.1523/JNEUROSCI.1871-19.2019
  • Research Articles, Cellular/Molecular
    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
    Honghua Zheng, Lin Jia, Chia-Chen Liu, Zhouyi Rong, Li Zhong, Longyu Yang, Xiao-Fen Chen, John D. Fryer, Xin Wang, Yun-wu Zhang, Huaxi Xu and Guojun Bu
    Journal of Neuroscience 11 January 2017, 37 (7) 1772-1784; DOI: https://doi.org/10.1523/JNEUROSCI.2459-16.2017
  • Research Articles, Neurobiology of Disease
    TREM2/DAP12 Signal Elicits Proinflammatory Response in Microglia and Exacerbates Neuropathic Pain
    Masaaki Kobayashi, Hiroyuki Konishi, Akira Sayo, Toshiyuki Takai and Hiroshi Kiyama
    Journal of Neuroscience 26 October 2016, 36 (43) 11138-11150; DOI: https://doi.org/10.1523/JNEUROSCI.1238-16.2016
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