Regular ArticleCellular transformation by SV40 large T antigen: interaction with host proteins
References (80)
- et al.
Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53
Virology
(1989) - et al.
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
Cell
(1988) - et al.
An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120
Cell
(1989) - et al.
Chaperone power in a virus? [letter]
Trends Biochem Sci
(1994) - et al.
The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus
Cell
(1989) - et al.
Cellular targets for transformation by the adenovirus E1A proteins
Cell
(1989) - et al.
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
Cell
(1991) - et al.
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
Cell
(1992) - et al.
SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family
Cell
(1989) - et al.
Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
Cell
(1979)
p53, the cellular gatekeeper for growth and division
Cell
(1997)
p53 function and dysfunction
Cell
(1992)
MDM2—arbiter of p53’s destruction
Trends Biochem Sci
(1997)
p300/MDM2 complexes participate in MDM2-mediated p53 degradation
Mol Cell
(1998)
p53-dependent apoptosis suppresses tumor growth and progression in vivo
Cell
(1994)
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
Mol Cell
(1998)
Recruitment of p300/CBP in p53-dependent signal pathways
Cell
(1997)
Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3-containing proapoptosis protein in the cytoplasm
J Biol Chem
(2000)
The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions
J Virol
(1989)
Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations
J Virol
(1993)
Transformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen
J Virol
(1992)
Association of p300 and CBP with simian virus 40 large T antigen
Mol Cell Biol
(1996)
p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigen
J Virol
(1997)
DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication
Genes Dev
(1997)
p53: puzzle and paradigm
Genes Dev
(1996)
Efficient transcriptional activation of many simple modular promoters by simian virus 40 large T antigen
J Virol
(1993)
TAF-like function of SV40 large T antigen
Genes Dev
(1996)
The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300
EMBO J
(1996)
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
Nature
(1986)
The RB family of cell cycle regulatory factors
J Cell Biochem
(1998)
Identification of a growth suppression domain within the retinoblastoma gene product
Genes Dev
(1992)
Subunit composition determines E2F DNA-binding site specificity
Mol Cell Biol
(1997)
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
[published erratum appears in Mol Cell Biol 1995;
(1995)
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
Nature
(1993)
Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo
Mol Cell Biol
(1989)
The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations
EMBO J
(1990)
Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product
Mol Cell Biol
(1990)
The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins
Mol Cell Biol
(1998)
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