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Roles for Serotonin in Neuroembryogenesis

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Book cover Serotonin

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 133))

Abstract

The idea that neurotransmitters such as serotonin (5-HT) might have non-transmitter functions during development has arisen from the observation in a number of species that these substances are present early in embryogenesis prior to the onset of synaptogenesis or neurotransmission. (Proposed functions for these early agents include the control of cell shape changes and morphogenetic cell movements during cleavage and gastrulation in sea urchins, fish, amphibians, birds and mammals; participation in the process of neurulation, torsion and flexure in chicks; and as humoral regulators of neuronal genesis in rats (Table 1).

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Authors and Affiliations

  1. Department of Anatomy, University of North Carolina School of Medicine, Chapel Hill, North Carolina, 27514, USA

    Jean M. Lauder, James A. Wallace & Helmut Krebs

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  1. Jean M. Lauder
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  1. The University of Texas Medical Branch, Galveston, Texas, USA

    Bernard Haber

  2. Veterans Administration Medical Center, Brockton, Massachusetts, USA

    Sabit Gabay

  3. Brown University Division of Psychiatry and Human Behavior, Providence, Rhode Island, USA

    Sabit Gabay

  4. University of Athens School of Medicine, Athens, Greece

    M. R. Issidorides  & S. G. A. Alivisatos  & 

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Lauder, J.M., Wallace, J.A., Krebs, H. (1981). Roles for Serotonin in Neuroembryogenesis. In: Haber, B., Gabay, S., Issidorides, M.R., Alivisatos, S.G.A. (eds) Serotonin. Advances in Experimental Medicine and Biology, vol 133. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3860-4_28

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