Neural correlates of novelty detection in pulse-type weakly electric fish

Summary

• 1. Evoked potentials (EPs) and single unit recordings from various electrosensory-processing regions of several pulse-type gymnotiform species were made to investigate neural activity patterns that could be associated with novelty detection.

• 2. Whereas the electrosensory afferents and cells in the ELL exhibited only minor changes in response size as stimuli were presented less frequently (novel stimuli), most units studied in the torus semicircularis (TS) showed very strong, increased responsiveness to stimuli presented less frequently relative to stimuli presented persistently (at every EOD event: Figs. 1, 2).

• 3. The responses of the TS were graded with respect to stimulus frequency (Fig. 3). The discrimination between novel and persistent stimuli by the TS occurred with stimuli presented transversely or longitudinally with respect to the fish's long axis, and regardless of the timing of the stimulus with respect to the fish's pacemaker-related signal (PS). When electrosensory novelties were presented persistently the responses of the TS rapidly habituated (Fig. 4). This may indicate that activity in this region of the TS is novelty related.

• 4. This novelty-related activity in the TS can be correlated with certain aspects of the fish's behavior, i.e., EOD interval length during a behavioral novelty response (Fig. 5). However, TS activity may continue to indicate the occurrence of electrosensory novelties after the behavior has habituated.

• 5. It is suggested that the novelty-related activity of the TS of these fish is necessary, but not sufficient, for the production of electrosensory novelty-induced behavioral responses. Lesions of the region of the TS containing the rapidly-habituating neurons abolished the electrosensory novelty response, but not that resulting from visual and auditory stimulation.