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Two neuronal retinal components of the electroretinogram c-wave

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Abstract

Although the rising phase of the b-wave seems to be generated mainly in the rod bipolar cells and the cone on-bipolar cells, the slow component of the electroretinogram, the c-wave, evidently originates in the Müller cells and the pigment epithelium. The c-wave has three components. One cornea-positive component derives from the pigment epithelium, while a distal cornea-negative component (slow PIII) and a proximal slow component originate in the Müller cells. This third proximal component of the c-wave differs between mammalian species: it is negative in the rat retina, positive in the rabbit and human retina and may be lacking in the cat retina.

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Hanitzsch, R., Lichtenberger, T. Two neuronal retinal components of the electroretinogram c-wave. Doc Ophthalmol 94, 275–285 (1997). https://doi.org/10.1007/BF02582985

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