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Past, Present and Future of Human Chromaffin Cells: Role in Physiology and Therapeutics

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Abstract

Chromaffin cells are neuroendocrine cells mainly found in the medulla of the adrenal gland. Most existing knowledge of these cells has been the outcome of extensive research performed in animals, mainly in the cow, cat, mouse and rat. However, some insight into the physiology of this neuroendocrine cell in humans has been gained. This review summarizes the main findings reported in human chromaffin cells under physiological or disease conditions and discusses the clinical implications of these results.

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Acknowledgments

AHV holds a fellowship award from the Universidad Autónoma de Madrid. This work was supported by a grant from the Ministerio de Ciencia y Tecnología No. BFU2008-01382/BFI awarded to AA.

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Authors and Affiliations

  1. Departamento de Farmacología y Terapéutica, Facultad de Medicina, Universidad Autónoma de Madrid, c/Arzobispo Morcillo 4, 28029, Madrid, Spain

    Alberto Pérez-Alvarez, Alicia Hernández-Vivanco & Almudena Albillos

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  1. Alberto Pérez-Alvarez
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  2. Alicia Hernández-Vivanco
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  3. Almudena Albillos
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Correspondence to Almudena Albillos.

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A commentary to this article can be found at doi:10.1007/s10571-010-9607-8.

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Pérez-Alvarez, A., Hernández-Vivanco, A. & Albillos, A. Past, Present and Future of Human Chromaffin Cells: Role in Physiology and Therapeutics. Cell Mol Neurobiol 30, 1407–1415 (2010). https://doi.org/10.1007/s10571-010-9582-0

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