Immediate effects of digit amputation on SI cortex in the raccoon: unmasking of inhibitory fields
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Cited by (70)
Facial macrosomatognosia and pain in a case of Wallenberg's syndrome: Selective effects of vestibular and transcutaneous stimulations
2012, NeuropsychologiaCitation Excerpt :It is likely that any acute reorganisation occurs not only at a cortical level but also at subcortical sites within the afferent pathway, including the spinal, trigeminal and thalamic levels (Borsook et al., 1998; Churchill, Arnold, & Garraghty, 2001; Furue, Katafuchi, & Yoshimura, 2004; Waite, 1984). Some cells that normally receive inputs from the removed body parts increase their receptive field size so that previously subliminal inputs from neighboring areas can excite them (Calford & Tweedale, 1988; Rassmusson & Turnbull, 1983). The changes in the perceived sizes of the lips and teeth could be therefore explained by the fact that the discharge pattern of cells with inputs from the surrounding non-anesthetized areas are interpreted centrally as a distortion in the representation of these body parts.
From maps to form to space: Touch and the body schema
2010, NeuropsychologiaSynaptic basis for developmental plasticity in somatosensory cortex
2004, Current Opinion in NeurobiologyEffects of temporary deafferentation on raccoon post-synaptic dorsal column neurons
2002, Brain ResearchCitation Excerpt :Of particular interest is a description of the starting point of reorganization, immediately after removal of afferents but before any structural changes could occur. The immediate effects of nerve transection on cerebral cortex have been studied [2,4,14,22]; however, these experiments often last several hours during which time some rapid structural changes might occur. An alternative approach has been to produce a temporary, reversible deafferentation using local anesthetic or cold block.
Dynamic representational plasticity in sensory cortex
2002, NeuroscienceCitation Excerpt :Early studies (Rasmusson, 1982; Kelahan and Doetsch, 1984) reported no short-term plasticity. Rasmusson stated that 92% of electrode penetrations did not find units with excitatory responses to somatosensory stimuli (Rasmusson, 1982); however around 50% of units sampled during recording sessions following digit amputation or ventral digit denervation had unusual inhibitory RFs (Rasmusson and Turnbull, 1983). Kelahan and Doetsch (1984) reported that within 1 day of digit 3 amputation, 49% of penetrations had responsive units, although the stimuli required to elicit responses were unusual.
Supported by the Medical Research Council of Canada.
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We gratefully acknowledge the assistance of H.K. Cunningham.