Elsevier

Brain Research

Volume 338, Issue 1, 8 July 1985, Pages 186-191
Brain Research

Morphology of peptide-containing neurons in the rat basolateral amygdaloid nucleus

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Abstract

The peroxidase-antiperoxidase (PAP) immunohistochemical technique was used to identify neurons in the basolateral amygdaloid nucleus (BL) that contain vasoactive intestinal polypeptide (VIP), somatostatin (SOM) or cholecystokinin (CCK). Examination of immunostained neurons demonstrated that most, if not all, of these peptide-containing cells correspond to spine-sparse class II neurons recognized in Golgi studies. Each type of peptide-containing perikaryon in BL exhibits a distinct size distribution which, in part, accounts for the broad size range of class II neurons noted in Golgi studies.

References (31)

  • RobertsG.W. et al.

    Distribution of neuropeptides in the limbic system of the rat: the amygdaloid complex

    Neuroscience

    (1982)
  • RobertsG.W. et al.

    Peptides, the limbic lobe and schizophrenia

    Brain Research

    (1983)
  • BeinfieldM.C.

    Cholecystokinin in the central nervous system: a minireview

    Neuropeptides

    (1983)
  • EmsonP.C. et al.

    Cholecystokinin and vasoactive intestinal polypeptide in the mammalian CNS: distribution and possible physiological roles

  • EmsonP.C. et al.

    Anatomical chemistry of the cerebral cortex

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    This work was supported by National Institutes of Health Grant NS19733.

    *

    The author is grateful for the excellent technical assistance of Peggy Sullivan and secretarial assistance of Judy Lawrence. The help of Dr. William T. McGowan with the statistical analysis is greatly appreciated.

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