Furosemide- and bumetanide-sensitive ion transport and volume control in primary astrocyte cultures from rat brain
References (63)
Specific drug sensitive transport pathways for chloride and potassium ions in steady-state Ehrlich mouse ascites tumor cells
Biochim. Biophys. Acta
(1982)Potassium permeability and volume control in isolated rat hepatocytes
Biochim. Biophys. Acta
(1983)- et al.
Glial fibrillary acidic protein (GFA) in normal neural cells and in pathological conditions
- et al.
Electrically silent cotransport of Na+, K+ and Cl− in Ehrlich cells
Biochim. Biophys. Acta
(1980) - et al.
Cellular heterogeneity in primary cultures of brain cells revealed by immunocytochemical localization of glutamine synthetase
Brain Research
(1984) - et al.
Volume regulation and metabolism of suspended C6 glioma cells: an in vitro model to study cytotoxic brain edema
Brain Research
(1983) Active accumulation and exchange transport of chloride in astroglial cells in culture
Biochim. Biophys. Acta
(1981)- et al.
Cation transport and membrane potential properties of primary astroglial cultures from neonatal rat brains
Brain Research
(1979) - et al.
A method using 3-O-methyl-d-glucose and phloretin for the determination of intracellular water space of cells in monolayer cultures
Anal. Biochem.
(1975) - et al.
The ionic basis of the membrane potential in a rat glial cell line
Brain Research
(1976)
Control of growth by intracellular potassium and sodium concentrations is relaxed in transformed 3T3 cells
Biochim. Biophys. Res. Commun.
Respiration and cell volume of primary cultured cerebral astrocytes in media of various osmolarities
Brain Research
Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture
Brain Research
Extracellular K+ accumulation in the central nervous system
Prog. Biophys. Molec. Biol.
Bumetanide-sensitive potassium transport and volume regulation in turkey erythrocytes
Biochim. Biophys. Acta
Differences in cation transport properties of primary astrocyte cultures from mouse and rat brain
Brain Research
Astrocytes in primary cultures: membrane potential characteristics reveal exclusive potassium conductance and potassium accumulator properties
Brain Research
Cl− transport in a glioma cell line: evidence for two transport mechanisms
Brain Research
The effect of acute hypoxia and hypercapnia on the ultrastructure of the central nervous system
Brain
Experimental cerebral concussion. I. An electron microscopic study
J. Neurosurg.
Swelling and ion uptake in cat cerebrocortical slices: control by neurotransmitters and ion transport mechanisms
Neurochem. Res.
Further studies on the K-dependent swelling of the primate cerebral cortex in vivo: the enzymatic basis of the K dependent transport of chloride
Neurochemistry
Adenosine-stimulated astroglial swelling in cat cerebral cortex in vivo with total inhibition by a non-diuretic acylaryloxyacid derivative
J. Neurosurg.
Astrocytes in primary culture have chemically activated sodium channels
J. Neurosci.
Cotransport systems in the brush border membrane of the human placenta
A further study of the fine structure and membrane properties of neuroglia in the optic nerve ofNecturus
J. Neurobiol.
Furosemide inhibition of chloride transport in human red blood cells
J. Gen. Physiol.
Volume regulation byAmphiuma red blood cells. The membrane potential and its implications regarding the nature of the ion-flux pathways
J. Gen. Physiol.
The glial fibrillary acidic (GFA) protein
Dissociation of neonatal rat brain by dispase for preparation of primary astrocyte cultures
Neurochem. Res.
Cerebral microvasculature in ischemia
Cited by (158)
Cell Volume Control in Healthy Brain and Neuropathologies
2018, Current Topics in MembranesCitation Excerpt :The secondary phase of adaptation to chronic hyperosmotic conditions involves the accumulation of idiogenic (compatible) organic osmolytes, which slowly replace the excess of inorganic ions within one or two weeks [see for example (Chan & Fishman, 1979; Lohr, McReynolds, Grimaldi, & Acara, 1988) and review (Gullans & Verbalis, 1993)]. In contrast to the whole brain, numerous studies in cultured and acutely isolated neurons (Aitken et al., 1998; Horie et al., 1989; Pasantes-Morales et al., 1993; Zhang & Bourque, 2003) and the majority of publications in cultured astrocytes [e.g., (Kimelberg & Frangakis, 1985; O'Connor et al., 1993)] found no evidence of RVI when cells have been exposed to hyperosmotic media for 10–90 min. Similarly, in brain slices prepared from either neocortex or hippocampus, pyramidal neurons and their dendritic trees shrunk under hyperosmotic conditions but did not demonstrate RVI, at least during incubation times under 1 h (Andrew & MacVicar, 1994; Andrew, Lobinowich, & Osehobo, 1997).
Turning down the volume: Astrocyte volume change in the generation and termination of epileptic seizures
2017, Neurobiology of DiseaseCitation Excerpt :As described above, astrocyte swelling may be a catalyst for inducing and/or augmenting seizures, so the following discussion will focus specifically on RVD subsequent to cell swelling. RVD has been repeatedly observed in cultured astrocytes swollen by hypoosmolar or high K+ media (Eriksson et al., 1992; Kimelberg and Frangakis, 1985; Olson et al., 1995; Vitarella et al., 1994). Disagreement exists as to whether astrocytic RVD occurs in intact tissue, as various groups have reported astrocytic swelling in brain slices without RVD (Andrew et al., 1997; Hirrlinger et al., 2008; Risher et al., 2009).
Mechanisms of Cell-Volume Regulation in the Central Nervous System
2017, Brain Edema: From Molecular Mechanisms to Clinical PracticeSodium dynamics: Another key to astroglial excitability?
2012, Trends in NeurosciencesCitation Excerpt :Another [Na+]i-dependent K+ transport system is represented by the Na+/K+/Cl− cotransporter NKCC1, which electroneutrally transports Na+, K+, and Cl− ions into and out of cells with a stoichiometry of 1Na+:1K+:2Cl−. Based on its pharmacological sensitivity to furosemide or bumetanide, the NKCC1 has been shown to operate functionally in cultured astrocytes [17,64] and in the rat optic nerve [65]; in the latter preparation its expression was also confirmed by immunostaining. Astroglial Na+/K+ ATPase has another important functional and homeostatic role: [Na+]i-dependent activation of the Na+/K+ ATPase initiates the astrocyte–neurone lactate shuttle that represents a universal mechanism for activity-dependent neuronal metabolic support [66].