Elsevier

Brain Research

Volume 381, Issue 2, 3 September 1986, Pages 351-355
Brain Research

Sub-second striatal dopamine release measured by in vivo voltammetry

https://doi.org/10.1016/0006-8993(86)90087-9Get rights and content

Abstract

High speed cyclic voltammetry was used to measure electrically stimulated striatal dopamine release in vivo with 25 mc time resolution. Dopamine release after 1 s stimulations was readily detectable and could be manipulated by drugs known to influence dopaminergic neurones. Using data-average dopamine release could be detected following stimulus trains as short as 100 ms. The use of carbon fibre microelectrodes gave a spatial resolution better than 5 μm.

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