Spontaneous activity of Type II but not Type I striatal neurons is correlated with recovery of behavioral function after dopamine-depleting brain lesions
References (26)
- et al.
Grafts of embryonic substantia nigra reinnervating the ventrolateral neostriatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway
Brain Research
(1981) - et al.
Sensorimotor impairments following localized kainic acid and 6-hydroxydopamine lesions of the neostriatum
Brain Research
(1982) - et al.
Simultaneous determination of catecholamines and unconjugated 3,4-dihydroxyphenylacetic acid (DOPAC) in brain tissue by ion-pairing reverse phase HPLC with electrochemical detection
Anal. Biochem.
(1980) - et al.
Long-term effects of dopamine-depleting brain lesions on spontaneous activity of Type II striatal neurons: relation to behavioral recovery
Brain Research
(1986) - et al.
Effects of intraventricular 6-hydroxydopamine on the dopaminergic innervation of striatum: histochemical and neurochemical analysis
Brain Research
(1986) - et al.
Short-term effects of dopamine-depleting brain lesions on spontaneous activity of striatal neurons: relation to local striatal dopamine levels and behavior
Brain Research
(1986) Motor functions of the striatum in the rat: critical role of the lateral region in tongue and forelimb reaching
Neuroscience
(1988)- et al.
Dopamine receptor changes following destruction of the nigrostriatal pathway: lack of a relationship to rotational behavior
Brain Research
(1981) - et al.
Functional organization of dopamine and serotonin receptors in the rat forebrain
- et al.
Depletion of brain noradrenaline and dopamine by 6-hydroxydopamine
Brit. J. Pharmacol.
(1971)
Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity
Science
Regional effects of amphetamine in neostriatum: single-unit responses in freely moving rat
Soc. Neurosci. Abstr.
High- and low-affinity states of striatal D2 receptors are not affected by 6-hydroxydopamine or chronic haloperidol treatment
J. Neurochem.
Cited by (18)
Firing dynamics and LFP oscillatory patterns in the dopamine-depleted striatum during maze learning
2014, Basal GangliaCitation Excerpt :In the dopamine-depleted striatum, the firing rates of task-activated MSNs were increased, relative to the control striatum, during both pre- and in-task periods throughout training, whereas the firing rates of the task-suppressed units were significantly different from the control side only during certain task periods and/or learning phases. Previous studies reported that striatal MSNs classified as types I and II respond differently to dopamine depletion: neurons in one group (type II) recover their pre-lesion firing rates, whereas neurons in the second population (type I) maintain high spontaneous firing rates [34]. These previous results suggest that the direct and indirect pathway neurons could be affected differentially by dopamine depletion and that the differences that we found between task-activated and task-suppressed MSNs could, themselves, be part of these two main projection subtypes.
Dopamine-mediated regulation of striatal neuronal and network interactions
2000, Trends in NeurosciencesAmphetamine effects on striatal neurons: Implications for models of dopamine function
1998, Neuroscience and Biobehavioral ReviewsCompensatory mechanisms in experimental and human parkinsonism: Towards a dynamic approach
1998, Progress in Neurobiology