Research reportThe role of norepinephrine in adult rat somatosensory (SmI) cortical metabolism and plasticity
References (72)
- et al.
Locus coeruleus stimulation decreases deoxyglucose uptake in ipsilateral mouse cerebral cortex
Brain Research
(1979) - et al.
Responses evoked in mouse and rat SI cortex by vibrissa stimulation
Neurosci. Lett.
(1976) - et al.
Trophic effects of brain areas on the developing cerebral cortex. I. Growth and histological organization of intrrocular grafts
Dev. Brain Res.
(1983) - et al.
Locus coeruleus input affects metabolism in physiologically activated rat barrel cortex
Brain Res. Bull.
(1987) Cholinergic denervation of rat neocortex results in sympathetic innervation
Exp. Neurol.
(1981)- et al.
Acetylcholine-rich neuronal grafts in the forebrain of rats: effects of environmental enrichment, neonatal noradrenaline depletion, host transplantation site and regional source of embryonic donor cells on grafts size and acetylcholinesterase-positive fibre outgrowth
Brain Research
(1986) - et al.
Barrels and columnar cortical organization: evidence from 2-deoxyglucose (2-DG) experiments
Brain Research
(1977) - et al.
Reinnervation of the partially deafferented hippocampus by compensatory collateral sprouting from spared cholinergic and noradrenergic afferents
Brain Research
(1983) Plasticity of the rat barrel system
- et al.
Morphology of Golgi-impregnated neurons in mouse cortical barrels following vibrissae damage at different postnatal ages
Brain Research
(1979)
Effects of bilateral lesions of the locus coeruleus and of neonatal administration of 6-hydroxydopamine on the concentration of individual proteins in rat brain
Brain Research
Locus coeruleus modulation of dorsal horn unit responses to cutaneous stimulation
Brain Research
Long-lasting suppression of firing of cortical neurons and decrease in cortical blood flow following train pulse stimulation of the locus coeruleus in the cat
Brain Research
Central correlates of peripheral pattern alterations in the trigeminal system of the rat. II. The effect of nerve section
Dev. Brain Res.
Dissociated cells of foetal rat pallium grown in culture medium supplemented with noradrenaline: effects on the expression of neuron-specific enolase and cell adhesion molecule L1
Neurosci. Lett.
The development of the vibrissal cortical column: a 2-deoxyglucose study
Neurosci. Lett.
Axonal transport of β-receptors during the response to axonal injury and repair in locus coeruleus neurons
Brain Research
Reserpine and the role of axonal transport in the independent regulation of pre- and post-synaptic β-adrenoreceptors
Brain Research
Abnormal sympathoadrenal function and plasma catecholamines in obese Zucker rats
Pharmacol. Biochem. Behav.
The organization of the catecholamine innervation of somatosensory cortex: the barrel field of the mouse
Brain Research
Modification of postnatal development of neocortex in rat brain with experimental deprivation of locus coeruleus
Brain Research
In defense of optical density ratios in 2-deoxyglucose autoradiography
Brain Research
Neonatal 6-hydroxydopamine attenuates the neural and behavioral effects of enriched rearing in the rat
Eur. J. Pharmacol.
Projections of the common fur of the muzzle upon the cortical area for mystacial vibrissae in rats dewhiskered since birth
Neurosci. Lett.
Analgesia produced by electrical stimulation of catecholamine nuclei in the rat brain
Brain Research
Multiwhisker stimulation and its effects on vibrissa units in rat SmI barrel cortex
Brain Research
Functional organization of mouse barrel cortex
Brain Research
Cortical noradrenaline depletion eliminates sparing of spatial learning after neonatal frontal cortex damage in the rat
Neurosci. Lett.
The effects of l-dopa on regional cerebral glucose utilization in rats with unilateral lesions of the substantia nigra
Brain Research
The structural organization of layer IV in the somatosensory region (SI) of mouse cerebral cortex
Brain Research
Noradrenaline and functional plasticity in kitten visual cortex: a re-examination
J. Physiol. (Lond.)
The effects of neonatal 6-hydroxydopamine treatment on morphological plasticity in the dentate gyrus of the rat following entorhinal lesions
J. Comp. Neurol.
Modulation of visual cortical plasticity by acetylcholine and noradrenaline
Nature (Lond.)
The effect of neonatal 6-hydroxydopamine treatment on synaptogenesis in the visual cortex of the rat
J. Comp. Neurol.
Laminar differences in sizes, shapes and response profiles of cutaneous receptive fields in the rat SI cortex
Exp. Brain Res.
Effects of 6-hdroxydopamine on visual deprivation in the kitten striate cortex
J. Neurosci.
Cited by (55)
Neurochemical correlates of functional plasticity in the mature cortex of the brain of rodents
2017, Behavioural Brain Research10 lessons learned by a misguided physician
2017, Physiology and BehaviorCitation Excerpt :Over the years, changes in my personal research interests, and to a lesser extent, current research funding and fashions, have led me into a wide variety of differing clinical and basic research areas. Those studies have covered areas as diverse as iatrogenic muscle fibrosis [64], biorhythms [65], dorsal spinal column stimulation [66], axonal transport [4], neural plasticity [5], brain transplantation [67], traumatic brain injury [68], autonomic function [10], neural regulation of energy and glucose homeostasis in obesity and diabetes [69], neuronal metabolic sensing [70,71], neural development and gene-environment interactions [59]. Although I have always suffered from a degree of attention deficit hyperactivity disorder, these diverse areas of research focus over a more than 50 year career are not really that unusual in our world.
The metabolic trinity, glucose–glycogen–lactate, links astrocytes and neurons in brain energetics, signaling, memory, and gene expression
2017, Neuroscience LettersCitation Excerpt :Astrocytes are known targets of the locus coeruleus, and they have α1-, α2-, β1- and β2-adrenergic receptors linked to different second messenger and signaling pathways that modulate their glucose transport, glycolysis, oxidative metabolism, glycogen synthesis and degradation, glutamate uptake, glutamine hydrolysis, and other activities; in general, these processes are stimulated in cultured astrocytes by receptor agonists, with the specific effects dependent on receptor subtypes and signaling pathways [29,32,33,50,51]. Noradrenergic pathway intervention can cause either a rise or fall in brain glucose utilization in animals, depending on condition (with or without stimulation), brain region, and the agonists or antagonists used to target adrenoceptor subtypes [36,38,40,59,60]. Stimulation of glycogenolysis by noradrenaline has a profound effect because even a severe energy crisis does not overwhelm its regulatory contributions; during ischemia and seizures more glycogen remains in the ipsilateral cerebral cortex after unilateral lesion of the locus coeruleus [27,35].
Methylphenidate modulates cerebral post-stroke reorganization
2006, NeuroImageUncertainty, neuromodulation, and attention
2005, Neuron