Hippocampal type I and type II corticosteroid receptor affinities are reduced in rats predisposed to develop amphetamine self-administration
References (34)
- et al.
Feedback action and tonic influence of corticosteroids on brain function: a concept arising from the heterogeneity of brain receptor systems
Psychoneuroendocrinology
(1987) - et al.
Abnormal cortisol response in Alzheimer's disease linked to hippocampal atrophy
Lancet 2
(1988) - et al.
Corticotropin-releasing hormone and pituitary-adrenocortical responses in chronically stressed rats
Reg. Peptides
(1988) - et al.
Influence of 6-OHDA lesion of central noradrenergic systems on corticosteroid receptors and neuroendocrine response to stress
Brain Research
(1990) - et al.
The development of the glucocorticoid receptor system in the rat limbic brain. I. Ontogeny and autoregulation
Dev. Brain Des.
(1985) - et al.
Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition to acquisition of amphetamine self-administration
Brain Research
(1990) - et al.
Corticosterone receptors decline in a site-specific manner in the aged rat
Brain Research
(1983) - et al.
Adrenal steroid type I and type II receptor binding: estimated of in vivo receptor number, occupancy, and activation with varying level of steroid
Brain Research
(1990) - et al.
Serotonin innervation and glucocorticoid binding in the hippocampus: relevance to depression
- et al.
Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor
Science
(1987)
Arousal and physiological toughness: implications for mental and physical health
Psychol. Rev.
Primary structure and expression of a functional human glucorticoid receptor cDNA
Nature
Corticosteroid inhibition of ACTH secretion
Endocr. Rev.
Reserpine-induced decrease in type I and type II corticosteroid receptors in neuronal and lymphoid tissues of adrenalectomized rts
Neuroendocrinology
Glucocorticoid negative feedback and glucocorticoid receptors after hippocampectomy in rats
Horm. Metab. Res.
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Differential effects of social defeat in rats with high and low locomotor response to novelty
2011, NeuroscienceCitation Excerpt :LR-C animals showed significantly higher GR mRNA expression in the dentate gyrus when compared to HR-C. This is consistent with previously reported data that LR animals have higher GR mRNA levels and higher corticosteroid receptor affinity than HR in the hippocampus (Maccari et al., 1991; Kabbaj et al., 2000, 2007). Direct microinjection of the glucocorticoid receptor antagonist RU38486 in the hippocampus significantly decreases anxiety-like behavior in LR in the light-dark box test, an indication that the GR levels in the hippocampus are directly correlated to anxiety-like behavior (Kabbaj et al., 2000), and might be implicated in the higher anxiety levels displayed by LR rats.
Locomotor response to novelty as a predictor of reactivity to aversive stimuli in the rat
2007, Brain ResearchCitation Excerpt :Differential reactivity to environmental novelty and to drugs of abuse between HR and LR appear to be related to hypothalamic–pituitary–adrenal (HPA) axis reactivity. For example, compared to LR, HR secrete corticosterone for a prolonged period of time following exposure to novelty (Piazza et al., 1991a), differentially express corticotrophin releasing hormone mRNA in the hypothalamic paraventricular nucleus central nucleus of the amygdala (Kabbaj et al., 2000) and exhibit lower affinities for hippocampal type I and II corticosteroid receptors, which are involved in corticosteroid negative feedback mechanisms (Maccari et al., 1991). Furthermore, HR are more sensitive to the reinforcing properties of corticosterone (Piazza et al., 1993).
Spontaneous appetence for wheel-running: a model of dependency on physical activity in rat
2006, European PsychiatryCitation Excerpt :In physiological terms, it has been shown that HR and LR rats differ in the response on their HPA axis to novel situations. HR rats present a prolonged increase in blood corticosterone levels, unlike LR rats [11,29]. Changes in the response to novel situations as a result of physical activity and the synchronization of circadian rhythms suggest that modifications may occur in the functioning of the HPA axis as a result of free physical activity, thus confirming the influence of physical activity on the HPA axis, as previously shown [5,8,14].
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This work was supported by la Fondation pour la Recherche Médicale. l'Institut National de la Santéet de la Recherche Médicale (INSERM) and l'Universitéde Bordeaux II.