Suprachiasmatic circadian pacemaker of rat shows two windows of sensitivity to neuropeptide Y in vitro

doi:10.1016/0006-8993(93)90166-K

Brain Research

Volume 620, Issue 2, 27 August 1993, Pages 281-286

https://doi.org/10.1016/0006-8993(93)90166-K Get rights and content

Abstract

The geniculohypothalamic tract carries visual information from the intergeniculate leaflet to the suprachiasmatic circadian pacemaker. NPY, found in this projection, has been shown to affect the phase of behavioral rhythms and influence photic entrainment. We now demonstrate that NPY, when briefly applied to the geniculate projection sites of rat SCN in vitro, induces permanent phase-shifts in the rhythm of neuronal electrical activity at two separate phases of the circadian cycle.

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: Support of AFOSR Grant 90-0205 to M.U.G. and NIH Grant T32 GMO7143 to M.M. is gratefully acknowledged.

^*: We would like to thank Dr. Eve Gallman and Angela J. McArthur for their helpful discussions.

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Suprachiasmatic circadian pacemaker of rat shows two windows of sensitivity to neuropeptide Y in vitro

Abstract

Neurosci. Lett.

Neurosci. Lett.

Brain Res.

Neuroscience

Brain Res. Bull.

Brain Res.

Physiol. Behav.

Brain Res. Bull.

Neurosci. Lett.

Brain Res.

Brain Res. Bull.

Neurosci. Lett.

Brain Res.

Brain Res.

Peptides

Brain Res.

Neurosci. Lett.

Neurosci. Lett.

Brain Res.

Brain Res.

Brain Res.

Life Sci.

Brain Res.

Response of hamster circadian system to transitions between light and darkness

Am. J. Physiol.

Neuropeptide Y in the hypothalamus: effects on corticosterone and single-unit activity

Am. J. Physiol.

Neuropeptide Y distribution in the rat brain

Science

Circadian phase-response curves for dark pulses in the hamster

J. Comp. Physiol.

Ventral lateral geniculate nucleus efferents to the rat suprachiasmatic nucleus exhibit avian pancreatic polypeptide-like immunoreactivity

J. Comp. Neurol.

Organization of the lateral geniculate-hypothalamic connections in the rat

J. Comp. Neurol.

Neuropeptide Y and human pancreatic polypeptide stimulate feeding behaviors in the rat

Endocrinology

An immunocytochemical study of the serotonergic innervation of the thalamus of the rat

J. Comp. Neurol.

Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system-II

Neuroscience

SCN electrophysiology in vitro