Effect of NMDA receptor antagonists on prostaglandin E2-induced hyperalgesia in conscious mice
References (41)
- et al.
The behavioral effects of an N-methylaspartate receptor antagonist following application to the lumbar spinal cord of conscious rats
Neuropharmacology
(1984) - et al.
Noxious stimulus-induced increase in spinal prostaglandin E2 is noradrenergic terminal-dependent
Neurosci. Lett.
(1990) - et al.
Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat
Neurosci. Lett.
(1991) - et al.
Excitatory amino acids and synaptic transmission: the evidence for a physiological function
Trends. Pharmacol. Sci.
(1990) - et al.
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype
J. Biol. Chem.
(1993) - et al.
Intrathecal morphine in mice: a new technique
Eur. J. Pharmacol.
(1980) - et al.
Intrathecal injection of acetylsalicylic acid, salicylic acid and indomethacin depresses C fiber-evoked activity in the rat thalamus and spinal cord
Pain
(1992) - et al.
Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice
Pain
(1994) - et al.
Antinociceptive actions of different classes of excitatory amino acid receptor antagonists in mice
Eur. J. Pharmacol.
(1992) - et al.
Differential effects of competitive and non-competitiveN-methyl-d-aspartate antagonists on glucose use in the limbic system
Neurosci. Lett.
(1988)
Activation of GABAA receptors in hypothalamus modulates PGF2α- or PGE2-induced catecholamine secretion in rats
Prostaglandins
Neurotransmitter candidates of somatosensory primary afferent fibers
Neuroscience
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype
J. Biol. Chem.
Indomethacin blocks central nociceptive effects of PGF2α
Brain Res.
Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2α to conscious mice
Brain Res.
Behavioral classification of excitatory acid receptors in mouse spinal cord
Eur. J. Pharmacol.
Cloning and expression of cDNA for a mouse prostaglandin E receptor EP1 subtype
J. Biol. Chem.
Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists
Trends Pharmacol. Sci.
Spinal pharmacology of thermal hyperesthesia induced by constriction injury of sciatic nerve. Excitatory amino acid antagonists
Pain
Nitric oxide and hippocampal synaptic plasticity
Biochem. Pharmacol.
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TRP-channels as key integrators of lipid pathways in nociceptive neurons
2014, Progress in Lipid ResearchCitation Excerpt :Deorphanizing of GPCRs is a promising approach for the identification of novel or formerly unrelated lipid receptors in sensory neurons and may open novel therapeutic perspectives for the development of analgesics. Even though EP and IP-receptor signaling can modulate postsynaptic AMPA- and NMDA-receptor activity [136–138] and endocannabinnoid signaling can modulate Cav-activity [139,140], TRP channels represent the biggest family of ion channels with known lipid GRPC dependent modulation. However, the role of lipid GPCRs in modulating other ligand- or voltage-gated ion channels, which are important for nociceptive processing, such as ASIC, HCN, ANO1, Piezos, TREK1, Nav and Kv, still remains to be elucidated.
Analgesic and anti-inflammatory activities of the ethanol extract of the leaves of Helianthus Annus in Wistar rats
2010, Asian Pacific Journal of Tropical MedicineInvolvement of NMDA receptor in nociceptive effects elicited by intrathecal [Tyr<sup>6</sup>] γ2-MSH(6-12), and the interaction with nociceptin/orphanin FQ in pain modulation in mice
2009, Brain ResearchCitation Excerpt :Intrathecal NMDA produced a significant decrease in the response latencies to noxious thermal stimulation (Aanonsen et al., 1990; Kolhekar et al., 1993; Meller et al., 1992a,b, 1996; Raigorodsky and Urca, 1987). Furthermore NMDA receptor may be involved in the hyperalgesic effects induced by some substances intrathecally, including histamine (Sakurada et al., 2002a), prostaglandin E2 (Nishihara et al., 1995), and α, β-methylene ATP (Tsuda et al., 1999). Our results showed that MrgC agonist [Tyr6]- γ2-MSH(6-12) administered intrathecally induced hyperalgesic effect in a dose-dependent manner.
Role of periaqueductal grey prostaglandin receptors in formalin-induced hyperalgesia
2006, European Journal of PharmacologyAntagonists and agonists at the glycine site of the NMDA receptor for therapeutic interventions
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