Full paperExpression of L1 and N-CAM cell adhesion molecules during development of the mouse olfactory system
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Transplantation of Olfactory Ensheathing Cells for Neural Repair
2015, Neural RegenerationIgSF8: A developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses
2012, Molecular and Cellular NeuroscienceCitation Excerpt :Cell adhesion molecules (CAMs) that belong to the Ig superfamily (IgSF) have documented roles in axon outgrowth and navigation (Maness and Schachner, 2007; Plachez and Richards, 2005). In the olfactory system Ig-containing CAMs such as neural cell adhesion molecule (NCAM), olfactory cell adhesion molecule (OCAM) and L1 have been implicated in regulating olfactory development (Miragall et al., 1989; Treloar et al., 1997; Yoshihara et al., 1997). Therefore we selected IgSF8 for further study to test the hypothesis that it has a role in the development of the olfactory pathway.
Encouraging regeneration in the central nervous system: Is there a role for olfactory ensheathing cells?
2011, Neuroscience ResearchOlfactory ensheathing cells: Biology in neural development and regeneration
2010, Progress in NeurobiologyCitation Excerpt :OECs, which envelop olfactory axons along their entire length and isolate them from other cells, are thought to support olfactory axonal extension by providing a favorable cellular substrate containing factors that facilitate axon binding and elongation (Doucette, 1990; Ramon-Cueto and Valverde, 1995; Tisay and Key, 1999; Kafitz and Greer, 1999). Cell adhesion molecules known to be involved in glia-axon adhesion, including NCAM, PSA-NCAM, and N-cadherin, are expressed at the surface of OECs at all developmental stages (Miragall et al., 1988, 1989; Key and Akeson, 1990; Franceschini and Barnett, 1996). OECs also produce a range of extracellular matrix proteins, such as laminin and fibronectin, which also facilitate axon outgrowth (Doucette, 1996; Gong and Shipley, 1996; Whitesides and LaMantia, 1996; Kafitz and Greer, 1997).